The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) and its
principal negative regulator, the E3 ligase adaptor Kelch-like ECH-associated protein 1 …

Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

The pathogenesis of Parkinson's disease (PD) remains unclear, and there is no disease-
modifying agent for PD. Withaferin A (WA), a naturally occurring compound, has emerged as …

Parkinson's disease (PD) is a complex multifactorial disorder that has been associated with
the processes of oxidative stress. In the absence of curative therapies, modification of the …

Parkinson's disease (PD) is a neurodegenerative disease with both genetic and sporadic
origins. In this study, we investigated the electrophysiological properties, synaptic activity …

Instead of the progress in the understanding of etiology of Parkinson's disease (PD),
effective methods to prevent the progression of the disease have not been developed and …

Neurodegenerative disorders are chronic brain diseases that affect humans worldwide.
Although many different factors are thought to be involved in the pathogenesis of these …

Abstract The Angiotensin II Receptor Blocker (ARB) Telmisartan reduces inflammation
through Angiotensin II AT1 receptor blockade and peroxisome proliferator-activated receptor …

Parkinson's disease (PD) is a progressive neurodegenerative disorder accompanied by a
selective loss of the dopamine (DA) ergic neurons residing in the substantia nigra. There is …

Protein transcription factor Nrf2 is a master regulator of cytoprotection. Nrf2 launches the
expression of more than 100 genes of antioxidant protection and xenobiotic detoxification …