Clinical and laboratory insights into the threat of hypervirulent Klebsiella pneumoniae

X Han, J Yao, J He, H Liu, Y Jiang, D Zhao… - International Journal of …, 2024 - Elsevier
Hypervirulent Klebsiella pneumoniae (hvKP) typically causes severe invasive infections
affecting multiple sites in healthy individuals. In the past, hvKP was characterized by a …

Hypervirulent Klebsiella pneumoniae

J Chen, H Zhang, X Liao - Infection and Drug Resistance, 2023 - Taylor & Francis
Hypervirulent Klebsiella pneumoniae (hvKP), especially multidrug-resistant hvKP (MDR-
hvKP) infections, are distributed globally, and lead to several outbreaks with high …

Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance

TA Russo, CL Alvarado, CJ Davies, ZJ Drayer… - Mbio, 2024 - Am Soc Microbiol
Distinguishing hypervirulent (hvKp) from classical Klebsiella pneumoniae (cKp) strains is
important for clinical care, surveillance, and research. Some combinations of iucA, iroB, peg …

Clonal background and routes of plasmid transmission underlie antimicrobial resistance features of bloodstream Klebsiella pneumoniae

OO Ikhimiukor, NI Zac Soligno, IJ Akintayo… - Nature …, 2024 - nature.com
Bloodstream infections caused by the opportunistic pathogen Klebsiella pneumoniae are
associated with adverse health complications and high mortality rates. Antimicrobial …

[HTML][HTML] Chasing the landscape for intrahospital transmission and evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae

L Liu, N Lou, Q Liang, W Xiao, G Teng, J Ma, H Zhang… - Science Bulletin, 2023 - Elsevier
The spread of hypervirulent carbapenem-resistant Klebsiella pneumoniae (Hv-CRKP) is a
global health concern. Here, we report the intrahospital colonization and spread of Hv …

Detection and characterization of putative hypervirulent Klebsiella pneumoniae isolates in microbiological diagnostics

B Neumann, C Stürhof, A Rath, B Kieninger, E Eger… - Scientific reports, 2023 - nature.com
Hypervirulent Klebsiella pneumoniae strains (hvKp) can cause invasive community-
acquired infections in healthy patients of all ages. In this study, the prevalence of putative …

Hypervirulent and carbapenem-resistant Klebsiella pneumoniae: A global public health threat

T Lei, B Liao, LR Yang, Y Wang, X Chen - Microbiological Research, 2024 - Elsevier
The evolution of hypervirulent and carbapenem-resistant Klebsiella pneumoniae can be
categorized into three main patterns: the evolution of KL1/KL2-hvKp strains into CR-hvKp …

From farm to fork: Persistence of clinically relevant multidrug-resistant and copper-tolerant klebsiella pneumoniae long after colistin withdrawal in poultry production

J Mourão, M Ribeiro-Almeida, C Novais… - Microbiology …, 2023 - Am Soc Microbiol
Concerns about colistin-resistant bacteria in animal food-environmental-human ecosystems
prompted the poultry sector to implement colistin restrictions and explore alternative trace …

The distribution characteristics of global blaOXA-carrying Klebsiella pneumoniae

L Meng, Z Liu, C Liu, C Li, H Shen, X Cao - BMC Infectious Diseases, 2023 - Springer
Objective To analyze the distribution of blaOXA among global Klebsiella pneumoniae and
the characteristics of blaOXA-carrying K. pneumoniae. Materials and Methods The genomes …

Increase in antioxidant capacity associated with the successful subclone of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11-KL64

R Wang, A Zhang, S Sun, G Yin, X Wu, Q Ding… - Nature …, 2024 - nature.com
The acquisition of exogenous mobile genetic material imposes an adaptive burden on
bacteria, whereas the adaptational evolution of virulence plasmids upon entry into …