In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)
P Sarma, N Shekhar, M Prajapat, P Avti… - Journal of …, 2021 - Taylor & Francis
The N terminal domain (NTD) of Nucleocapsid protein (N protein) of coronavirus (CoV)
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex …
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex …
Taste mechanism of umami peptides from Chinese traditional fermented fish (Chouguiyu) based on molecular docking using umami receptor T1R1/T1R3
D Yang, C Li, L Li, S Chen, X Hu, H Xiang - Food chemistry, 2022 - Elsevier
Umami peptides formed during fermentation of Chouguiyu contribute to its unique taste. In
this study, the umami taste of peptide extract from Chouguiyu was improved after …
this study, the umami taste of peptide extract from Chouguiyu was improved after …
Molecular dynamics simulation and pharmacokinetics studies of ombuin and quercetin against human pancreatic α-amylase
Diabetes mellitus (DM) is a group of metabolic disorders characterised by chronic
hyperglycaemia. DM is currently one of the top ten causes of death in humans. Chronic …
hyperglycaemia. DM is currently one of the top ten causes of death in humans. Chronic …
Rational drug design and synthesis of molecules targeting the angiotensin II type 1 and type 2 receptors
The angiotensin II (Ang II) type 1 and type 2 receptors (AT1R and AT2R) orchestrate an
array of biological processes that regulate human health. Aberrant function of these …
array of biological processes that regulate human health. Aberrant function of these …
Identification of umami peptides from Wuding chicken by Nano-HPLC-MS/MS and insights into the umami taste mechanisms
R Jia, Y He, G Liao, Z Yang, D Gu, Y Pu… - Food Research …, 2023 - Elsevier
Wuding chicken is popular with consumers in China because of its umami taste. This study
aimed to identify novel umami peptides from Wuding chicken and explore the taste …
aimed to identify novel umami peptides from Wuding chicken and explore the taste …
In silico molecular studies of natural compounds as possible anti-Alzheimer's agents: ligand-based design
O Iwaloye, OO Elekofehinti, AI Momoh… - … Modeling Analysis in …, 2020 - Springer
Alzheimer disease (AD) is the most common form of dementia contributing to about 60–70%
of cases. β-Site amyloid precursor protein cleaving enzyme-1 (BACE1) plays an important …
of cases. β-Site amyloid precursor protein cleaving enzyme-1 (BACE1) plays an important …
Therapeutic potential of Chromolaena odorata phyto-constituents against human pancreatic α-amylase
Abstract Type II Diabetes Mellitus (DM) is caused by insulin resistance in peripheral tissue
and impaired insulin secretion through a dysfunction of the pancreatic β-cell. Acarbose is an …
and impaired insulin secretion through a dysfunction of the pancreatic β-cell. Acarbose is an …
Peptidomics Screening and Molecular Docking with Umami Receptors T1R1/T1R3 of Novel Umami Peptides from Oyster (Crassostrea gigas) Hydrolysates
J Zhang, Z Tu, P Wen, H Wang… - Journal of Agricultural and …, 2023 - ACS Publications
In this study, novel umami peptides were prepared from oyster (Crassostrea gigas)
hydrolysates, and their umami mechanisms were investigated. Umami fractions G2 and G3 …
hydrolysates, and their umami mechanisms were investigated. Umami fractions G2 and G3 …
Excavation, identification and structure-activity relationship of heat-stable umami peptides in the processing of Wuding chicken
R Jia, Y Yang, G Liao, D Gu, Y Pu, M Huang, G Wang - Food Chemistry, 2024 - Elsevier
Umami peptides from different stages of Wuding chicken processing were discovered,
isolated, and purified using ultrafiltration membrane, gel filtration chromatography, and …
isolated, and purified using ultrafiltration membrane, gel filtration chromatography, and …
Potentiality of Moringa oleifera against SARS-CoV-2: identified by a rational computer aided drug design method
D Sen, S Bhaumik, P Debnath… - Journal of Biomolecular …, 2022 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) has created a global human health crisis
and economic setbacks. Lack of specific therapeutics and limited treatment options against …
and economic setbacks. Lack of specific therapeutics and limited treatment options against …