Beetles as model organisms in physiological, biomedical and environmental studies–a review

Z Adamski, SA Bufo, S Chowański, P Falabella… - Frontiers in …, 2019 - frontiersin.org
Model organisms are often used in biological, medical and environmental research. Among
insects, Drosophila melanogaster, Galleria mellonella, Apis mellifera, Bombyx mori …

Acetylcholinesterase: a primary target for drugs and insecticides

S Thapa, M Lv, H Xu - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background: Acetylcholinesterase is a serine hydrolase that terminates the action of the
neurotransmitter acetylcholine by hydrolyzing it into acetic acid and choline. Objective: The …

De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus)

IW Kim, JH Lee, S Subramaniyam, EY Yun, I Kim… - PLoS …, 2016 - journals.plos.org
Cockroaches are surrogate hosts for microbes that cause many human diseases. In spite of
their generally destructive nature, cockroaches have recently been found to harbor …

Recent advances on the influence of fipronil on insect behavior

ME Rosa, RS Oliveira, R de Faria Barbosa… - Current Opinion in Insect …, 2024 - Elsevier
Fipronil, a pesticide widely used to control agricultural and household insect pests, blocks
insect GABA A and glutamate (GluCl) ionotropic receptors, resulting in uncontrolled …

Biochemical and behavioral deficits in the lobster cockroach Nauphoeta cinerea model of methylmercury exposure

IA Adedara, DB Rosemberg, DO Souza… - Toxicology …, 2015 - academic.oup.com
Methylmercury (MeHg) is well-known for its neurodevelopmental effects both in animals and
in humans. As an alternative to utilizing conventional animal models, this study evaluated …

[HTML][HTML] Utility of cockroach as a model organism in the assessment of toxicological impacts of environmental pollutants

IA Adedara, KA Mohammed, OF Da-Silva… - Environmental …, 2022 - Elsevier
Environmental pollution is a global concern because of its associated risks to human health
and ecosystem. The bio-monitoring of environmental health has attracted much attention in …

The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases

A Abd-Ella, M Stankiewicz, K Mikulska, W Nowak… - PloS one, 2015 - journals.plos.org
Insect vector-borne diseases remain one of the principal causes of human mortality. In
addition to conventional measures of insect control, repellents continue to be the mainstay …

Neurobehavioral and biochemical changes in Nauphoeta cinerea following dietary exposure to chlorpyrifos

IA Adedara, DB Rosemberg, D de Souza… - Pesticide biochemistry …, 2016 - Elsevier
The present study aimed to increase our understanding about the mode of toxic action of
organophosphate pesticides in insects by evaluating the biochemical and neurobehavioral …

[HTML][HTML] Central and peripheral neurotoxicity induced by the Jack Bean Urease (JBU) in Nauphoeta cinerea cockroaches

T Carrazoni, M de Avila Heberle, APA Perin… - Toxicology, 2016 - Elsevier
Abstract Background Ureases of Canavalia ensiformis are natural insecticides with a still
elusive entomotoxic mode of action. We have investigated the mechanisms involved in the …

[PDF][PDF] Phoneutria nigriventer venom and toxins: a review

ME De Lima, SG Figueiredo, A Matavel… - Spider …, 2015 - researchgate.net
The venom of Phoneutria nigriventer spider has been extensively studied. It is highly
neurotoxic, with clinical manifestations occurring a few minutes after the bite, mainly in …