Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …

Simple Summary Glioblastoma is the most common malignant brain tumor associated with a
poor prognosis, with a median survival of 14 months. Despite initial treatment with surgery …

Tumors reprogram their metabolism to generate complex neoplastic ecosystems. Here, we
demonstrate that glioblastoma (GBM) stem cells (GSCs) display elevated activity of the …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Glioblastoma (GBM) is the most common and lethal primary brain tumor. The standard
treatment for newly diagnosed GBM includes surgical resection, when feasible, followed by …

Temozolomide (TMZ) represents a standard-of-care chemotherapeutic agent in
glioblastoma (GBM). However, the development of drug resistance constitutes a significant …

Angiogenic growth factors (AGFs) are a class of secreted cytokines related to angiogenesis
that mainly include vascular endothelial growth factors (VEGFs), stromal-derived factor-1 …

Nerve growth factor (NGF) and its receptor, tropomyosin kinase receptor kinase type A
(TrkA) is emerging as an important target for Glioblastoma (GBM) treatment. TrkA is the …

Reports on the cytotoxicity of diamond nanoparticles (ND) are ambiguous and depend on
the physicochemical properties of the material and the tested cell lines. Thus, the aim of this …

In the last decade, many small molecules, usually characterized by heterocyclic scaffolds,
have been designed and synthesized as tyrosine kinase inhibitors (TKIs). Among them …