Introduction Paracetamol is a common agent taken in deliberate self‐poisoning and in
accidental overdose in adults and children. Paracetamol poisoning is the commonest cause …

Background Poisoning is one of the leading causes of admission to the emergency
department and intensive care unit. A large number of epidemiological changes have …

Background A local increase in angiotensin 2 after inactivation of angiotensin-converting
enzyme 2 by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce a …

Introduction Paracetamol is one of the most used medicines worldwide and is the most
common important poisoning in high-income countries. In overdose, paracetamol causes …

Acetaminophen is a commonly used analgesic and antipyretic agent and in recommended
therapeutic doses, is safe in healthy individuals. Because of wide availability and minimal …

Paracetamol (acetaminophen) was marketed in the 1950s as a nonprescription
analgesic/antipyretic without any preclinical toxicity studies. It became used increasingly for …

Paracetamol poisoning was first reported in 1966. The development of antidotes followed
within 10 years, and by 1980 acetylcysteine (NAC) was acknowledged as the optimal …

Background Anaphylactoid reactions to intravenous (IV) N-acetylcysteine (NAC) are well-
recognized adverse events during treatment for acetaminophen (APAP) poisoning …

Background Previous studies of paracetamol overdose treatment show that a 2-bag, 20-h
intravenous (IV) acetylcysteine regimen decreased the incidence of non-allergic …

Introduction Acetaminophen (paracetamol) is a commonly used analgesic and antipyretic
agent, which is safe in therapeutic doses. Acetaminophen poisoning due to self-harm or …