Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …

Question Should patients with imaging suggestive of low grade glioma (LGG) undergo
observation versus treatment involving a surgical procedure? Target population These …

Object The spontaneous prognostic factors and optimal therapeutic strategy for WHO Grade
II gliomas (GIIGs) have yet to be unanimously defined. Specifically, the role of resection is …

Background Total or subtotal surgical resection of WHO grade II glioma (diffuse low-grade
glioma, DLGG) can significantly increase survival. Moreover, a supratotal resection, ie, an …

The finding that most grades II and III gliomas harbor isocitrate dehydrogenase (IDH)
mutations conveying a relatively favorable and fairly similar prognosis in both tumor grades …

Background Awake surgery with intraoperative electrical mapping emerged as a gold-
standard approach in newly diagnosed diffuse low-grade glioma (DLGG) to optimize the …

Radiologically suspected low-grade gliomas (LGG) represent a special challenge for the
neurosurgeon during surgery due to their histopathological heterogeneity and indefinite …

Background Supratentorial diffuse low-grade gliomas present a slow macroscopic tumor
growth that can be quantified through the measurement of their velocity of diametric …

BACKGROUND Therapeutic strategy concerning incidental low-grade glioma (ILGG) is still
debated. Early “prophylactic” surgery has been proposed in asymptomatic patients with …

Objective Studies on the presenting symptoms of glioma in adults in the age of readily
available MRI imaging are scarce. This study investigates presenting symptoms of glioma …