The role of FTO variant rs1421085 in the relationship with obesity: A systematic review and meta-analysis

L Najd-Hassan-Bonab, M Safarpour… - Eating and Weight …, 2022 - Springer
Purpose Fat mass and obesity-associated (FTO) is considered the first locus associated with
adiposity, a concerning health problem worldwide. Many studies have evaluated the …

Serum C-peptide level and the risk of cardiovascular diseases mortality and all-cause mortality: A meta-analysis and systematic review

H Ahmadirad, F Teymoori, E Mokhtari… - Frontiers in …, 2023 - frontiersin.org
Aims and background Recently, the serum of C-peptide has been the focus of researchers
as a possible predictor of mortality. However, the possible association of serum C-peptide …

A wide range of missing imputation approaches in longitudinal data: a simulation study and real data analysis

M Jahangiri, A Kazemnejad, KS Goldfeld… - BMC Medical Research …, 2023 - Springer
Background Missing data is a pervasive problem in longitudinal data analysis. Several
single-imputation (SI) and multiple-imputation (MI) approaches have been proposed to …

Evaluating machine learning-powered classification algorithms which utilize variants in the GCKR gene to predict metabolic syndrome: Tehran Cardio-metabolic …

M Akbarzadeh, N Alipour, H Moheimani… - Journal of Translational …, 2022 - Springer
Abstract Background Metabolic syndrome (MetS) is a prevalent multifactorial disorder that
can increase the risk of developing diabetes, cardiovascular diseases, and cancer. We …

The AGT epistasis pattern proposed a novel role for ZBED9 in regulating blood pressure: Tehran Cardiometabolic genetic study (TCGS)

M Akbarzadeh, P Riahi, G Kolifarhood, H Lanjanian… - Gene, 2022 - Elsevier
Introduction High blood pressure is widely regarded as the most important risk factor for
cardiovascular diseases. Epistasis analysis may provide additional insight into the genetic …

The Tehran longitudinal family-based cardiometabolic cohort study sheds new light on dyslipidemia transmission patterns

M Akbarzadeh, P Riahi, AH Saeidian, M Zarkesh… - Scientific Reports, 2024 - nature.com
Dyslipidemia, as a metabolic risk factor, with the strongest and most heritable independent
cause of cardiovascular diseases worldwide. We investigated the familial transmission …

Genome-wide association study on blood pressure traits in the Iranian population suggests ZBED9 as a new locus for hypertension

G Kolifarhood, S Sabour, M Akbarzadeh… - Scientific Reports, 2021 - nature.com
High blood pressure is the heritable risk factor for cardiovascular and kidney diseases.
Genome-wide association studies (GWAS) on blood pressure traits increase our …

[HTML][HTML] Regularized machine learning models for prediction of metabolic syndrome using GCKR, APOA5, and BUD13 gene variants: Tehran cardiometabolic genetic …

N Alipour, A Kazemnejad, M Akbarzadeh… - Cell Journal …, 2023 - ncbi.nlm.nih.gov
Objective: Metabolic syndrome (MetS) is a complex multifactorial disorder that considerably
burdens healthcare systems. We aim to classify MetS using regularized machine learning …

Parental transmission plays the major role in high aggregation of type 2 diabetes in Iranian families: Tehran Lipid and Glucose Study

M Akbarzadeh, P Riahi, A Ramezankhani… - Canadian Journal of …, 2022 - Elsevier
Background This study is the first to evaluate familial aggregation, heritability and
inheritance mode of type 2 diabetes (T2D) in Tehran Lipid Glucose Study (TLGS) …

[HTML][HTML] Contributions and implications of the Tehran lipid and glucose study

F Azizi, M Takyar, A Zadeh-Vakili - International Journal of …, 2018 - ncbi.nlm.nih.gov
Abstract Tehran Lipid and Glucose Study (TLGS), an epidemiological study of non-
communicable disease with 20 years follow up in a developing country in nutrition transition …