Clinical spectrum of chronic acquired demyelinating polyneuropathies

DS Saperstein, JS Katz, AA Amato… - Muscle & Nerve …, 2001 - Wiley Online Library
A number of presentations of chronic demyelinating polyneuropathy have been identified,
each distinguished by its phenotypic pattern. In addition to classic chronic inflammatory …

Amyotrophic lateral sclerosis (ALS): a phylogenetic disease of the corticomotoneuron?

A Eisen, S Kim, B Pant - Muscle & nerve, 1992 - Wiley Online Library
It is proposed that the primary cell involved in amyotrophic lateral sclerosis (ALS) is the
corticomotoneuron. The spinal motoneuron becomes affected as a result of antegrade …

Immunologic reactions in amyotrophic lateral sclerosis brain and spinal cord tissue.

T Kawamata, H Akiyama, T Yamada… - The American journal of …, 1992 - ncbi.nlm.nih.gov
Expression of proteins associated with immune function was investigated
immunohistochemically in postmortem brain and spinal cord of patients with amyotrophic …

Intravenous immunoglobulin therapy in multifocal motor neuropathy: a double-blind, placebo-controlled study

JM Léger, B Chassande, L Musset, V Meininger… - Brain, 2001 - academic.oup.com
We conducted a double-blind, placebo-controlled, study of 19 patients fulfilling eligibility
criteria for multifocal motor neuropathy with persistent conduction block. They were enrolled …

Frequency and clinical correlates of anti–neural IgM antibodies in neuropathy associated with IgM monoclonal gammopathy

E Nobile‐Orazio, E Manfredini, M Carpo… - Annals of Neurology …, 1994 - Wiley Online Library
We studied the frequency and clinical correlates of different IgM specificities in 75 patients
with neuropathy associated with IgM monoclonal gammopathy. Patients were tested for IgM …

Neuropathies associated with paraproteinemia

AH Ropper, KC Gorson - New England Journal of Medicine, 1998 - Mass Medical Soc
A number of common disorders of the peripheral nervous system, termed paraproteinemic
neuropathies, are closely connected with the presence of excessive amounts of an …

Multifocal motor neuropathy

E Nobile-Orazio - Journal of neuroimmunology, 2001 - Elsevier
Multifocal motor neuropathy (MMN) is a recently identified peripheral nerve disorder
characterized by progressive, predominantly distal, asymmetric limb weakness mostly …

Elevated serum titers of proinflammatory cytokines and CNS autoantibodies in patients with chronic spinal cord injury

KC Hayes, TCL Hull, GA Delaney, PJ Potter… - Journal of …, 2002 - liebertpub.com
This study characterized the proinflammatory cytokines, interleukin-2 (IL-2) and tumor
necrosis factor alpha (TNF α), the antiinflammatory cytokines, IL-4 and IL-10, autoantibodies …

Pure motor demyelinating neuropathy: deterioration after steroid treatment and improvement with intravenous immunoglobulin.

M Donaghy, KR Mills, SJ Boniface… - Journal of Neurology …, 1994 - jnnp.bmj.com
Within one month of starting oral prednisolone treatment weakness unexpectedly increased
in four patients aged 34 to 75 years with purely motor forms of acquired chronic …

Antibodies against GM1 ganglioside affect K+ and NA+ currents in isolated rat myelinated nerve fibers

T Takigawa, H Yasuda, R Kikkawa… - Annals of Neurology …, 1995 - Wiley Online Library
High titers of anti‐GM1 ganglioside antibodies (anti‐GM1 antibodies) may be implicated in
lower motor neuron disease. We studied the pathogenic role of anti‐GM1 antibody using the …