An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …

Adversity in childhood is linked to mental and physical health throughout life Page 1 TOXIC
STRESS AND PTSD IN CHILDREN Adversity in childhood is linked to mental and physical …

Two extant frameworks–the harshness-unpredictability model and the threat-deprivation
model–attempt to explain which dimensions of adversity have distinct influences on …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …

Barbie or Lego? Reading maps or reading emotions? Do you have a female brain or a male
brain? Or is that the wrong question? On a daily basis we face deeply ingrained beliefs that …

Despite long-standing interest in the influence of adverse early experiences on mental
health, systematic scientific inquiry into childhood adversity and developmental outcomes …

A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …

The brain is a vital organ, susceptible to alterations under genetic influences and
environmental experiences. Social isolation (SI) acts as a stressor which results in …