Molecular Biomarkers for Cardiometabolic Disease: Risk Assessment in Young Individuals

UA Tahir, RE Gerszten - Circulation research, 2023 - Am Heart Assoc
Cardiometabolic diseases, including cardiovascular disease and diabetes, are major
causes of morbidity and mortality worldwide. Despite progress in prevention and treatment …

A scoping review of protein biomarkers for schizophrenia: state of progress, underlying biology, and methodological considerations

CHSF Berdeville, D Silva-Amaral… - Neuroscience & …, 2024 - Elsevier
Schizophrenia is characterized by symptoms such as delusions, hallucinations, and
avolition. The diagnosis is clinical, based on interviews and the main treatment involves …

C-reactive protein level and the genetic variant rs1130864 in the CRP gene as prognostic factors for 10-year cardiovascular outcome

S Schulz, S Rehm, A Schlitt, M Lierath, H Lüdike… - Cells, 2023 - mdpi.com
Background: Cardiovascular disease (CVD) is the primary cause of premature death and
disability worldwide. There is extensive evidence that inflammation represents an important …

Estimation of life's essential 8 score with incomplete data of individual metrics

Y Zheng, T Huang, M Guasch-Ferre, J Hart… - Frontiers in …, 2023 - frontiersin.org
Background The American Heart Association's Life's Essential 8 (LE8) is an updated
construct of cardiovascular health (CVH), including blood pressure, lipids, glucose, body …

Implications of metabolism on multi‐systems healthy aging across the lifespan

S Yao, LA Colangelo, AS Perry, MM Marron, K Yaffe… - Aging cell, 2024 - Wiley Online Library
Aging is increasingly thought to involve dysregulation of metabolism in multiple organ
systems that culminate in decreased functional capacity and morbidity. Here, we seek to …

Analysis of C-reactive protein from finger stick dried blood spot to predict high risk of cardiovascular disease

MY Schakelaar, H Kemperman, AH Schoneveld… - Scientific Reports, 2023 - nature.com
C-reactive protein (CRP) is an acute-phase protein involved in inflammation. Furthermore,
CRP is an important biomarker used in diagnostics to predict risk of cardiovascular disease …

Synergistic effects of glucose tolerance and BMI on cardiovascular events and all-cause mortality in a healthy population: CA. ME. LI. A study 7 years follow-up

M Bignotto, E Bianco, L Centofanti… - American Journal …, 2024 - journals.physiology.org
The CA. ME. LI. A (CArdiovascular risks, MEtabolic syndrome, LIver and Autoimmune
disease) epidemiological study was conducted in Abbiategrasso (Milan, Italy) to identify risk …

Is there a cost to caring? Dispositional affective empathy interacts with depressive symptoms to predict higher C-reactive protein 8 years later

EM Manczak - Biological psychology, 2023 - Elsevier
Affective empathy, including the tendency to vicariously experience the emotions of others,
is a highly-valued prosocial trait, but has been previously found to be associated with higher …

FCGR2A-HH Gene Variants Encoding the Fc Gamma Receptor for the C-Reactive Protein Are Associated with Enhanced Monocyte CD32 Expression and …

P Paul, C Picard, L Lyonnet, N Resseguier, L Hubert… - Biomedicines, 2022 - mdpi.com
Fcγ receptors (FcγRs) interact with the C-reactive protein (CRP) and mediate activation of
inflammation-related pathogenic mechanisms affecting cardiovascular health. Our study …

[HTML][HTML] Role of C-reactive protein in disease progression, diagnosis and management

S Ali, A Zehra, MU Khalid, M Hassan, SIA Shah - Discoveries, 2023 - pmc.ncbi.nlm.nih.gov
C-reactive protein (CRP) is a ring-shaped pentameric protein synthesized in the liver via
CRP gene transcription. It is an inflammatory marker, whose serum levels can be measured …