Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic
profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes …

Despite numerous research efforts, drug delivery through the oral route remains a major
challenge to formulation scientists. The oral delivery of drugs poses a significant challenge …

Sorafenib (SOR) is an oral multikinase inhibitor that effectively hampers the growth and
spread of cancer cells by targeting angiogenesis and proliferation. However, SOR tablets …

Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …

Conventional cyclodextrin complexation enhances the solubility of poorly soluble drugs but
is solvent-intensive and environmentally unfavorable. This study evaluated solvent-free hot …

Aim: To develop hyaluronic acid (HA)-coated poly-lactic-co-glycolic acid (PLGA)-
polysarcosine (PSAR) coupled sorafenib tosylate (SF) polymeric nanoparticles for targeted …

Silymarin (SIL) is a poorly water-soluble flavonoid reported for different pharmacological
properties. Its therapeutic applications are limited due to poor water solubility. In this study …

Pterostilbene (PTS) is a naturally occurring phytoalexin. PTS displays limited water
solubility, which consequently results in its diminished oral bioavailability. Therefore, a …

Albendazole is the preferred deworming drug and has strong insecticidal effects on human
and animal helminth parasites, showing remarkable activity against hepatocellular …

Febuxostat (FBX), a potent xanthine oxidase inhibitor, is widely used as a blood uric acid-
reducing agent and has recently shown a promising repurposing outcome as an anti-cancer …