Strategies to combat multidrug-resistant and persistent infectious diseases

O Pacios, L Blasco, I Bleriot, L Fernandez-Garcia… - Antibiotics, 2020 - mdpi.com
Antibiotic failure is one of the most worrying health problems worldwide. We are currently
facing an international crisis with several problematic facets: new antibiotics are no longer …

Farnesol and Tyrosol: Secondary Metabolites with a Crucial quorum-sensing Role in Candida Biofilm Development

CF Rodrigues, L Černáková - Genes, 2020 - mdpi.com
When living in biological and interactive communities, microorganisms use quorum-sensing
mechanisms for their communication. According to cell density, bacteria and fungi can …

Potential application of postbiotics metabolites from bioprotective culture to fabricate bacterial nanocellulose based antimicrobial packaging material

R Mohammadi, M Moradi, H Tajik, R Molaei - International Journal of …, 2022 - Elsevier
Postbiotics (P) of FreshQ, a food protective culture, was prepared and used to develop an
antimicrobial membrane by bacterial nanocellulose (BNC). Postbiotics were prepared in de …

Age is just a number: progress and obstacles in the discovery of new candidate drugs for sarcopenia

HJ Kim, DW Jung, DR Williams - Cells, 2023 - mdpi.com
Sarcopenia is a disease characterized by the progressive loss of skeletal muscle mass and
function that occurs with aging. The progression of sarcopenia is correlated with the onset of …

Farnesol exerts protective effects against chronic sleep deprivation‐induced cognitive impairment via activation SIRT1/Nrf2 pathway in the hippocampi of adult mice

Y Li, Z Xie, X Luo, X Wang, Y Wang… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Sleep deprivation (SD) negatively affects all aspects of health, with one serious
consequence being impaired cognition. Farnesol (FOL) is a sesquiterpene synthesized by …

Farnesol: An approach on biofilms and nanotechnology

AF Costa, LC Silva, AC Amaral - Medical Mycology, 2021 - academic.oup.com
Biofilms are important virulence factor in infections caused by microorganisms because of its
complex structure, which provide resistance to conventional antimicrobials. Strategies …

Inhibition of the pqsABCDE and pqsH in the pqs quorum sensing system and related virulence factors of the Pseudomonas aeruginosa PAO1 strain by farnesol

WR Li, TH Zeng, XB Xie, QS Shi, CL Li - International Biodeterioration & …, 2020 - Elsevier
Abstract Farnesol, a 15-carbon, naturally occurring sesquiterpene alcohol, exists widely in
plants and Candida albicans. It inhibits the production of the Pseudomonas Quinolone …

Phosphorylation of metabolites involved in salvage pathways for isoprenoid biosynthesis in plants

A Hemmerlin - Kinases and Phosphatases, 2023 - mdpi.com
The recycling of metabolic products is a major way to reduce the energy cost of de novo
biosynthesis. The salvage pathways involved not only regain a metabolic product but also …

Fusel oil: chemical composition and an overview of its potential application

TB Massa, DT Raspe, MC Feiten… - Journal of the Brazilian …, 2023 - SciELO Brasil
Fusel oil (FO) is one of the by-products of the sugar-alcohol industry, which has application
as an additional source of higher alcohols for the production of esters with flavoring, fuels …

[HTML][HTML] Inhibiting roles of farnesol and HOG in morphological switching of Candida albicans

X Wang, H He, J Liu, S Xie, J Han - American Journal of …, 2020 - ncbi.nlm.nih.gov
Candida albicans is a major opportunistic fungal pathogen of humans, especially in the oral
cavity it involves in precancerous lesions. Numerous transcriptional regulators and hypha …