Interstitial cystitis/bladder pain syndrome: the evolving landscape, animal models and future perspectives

Y Akiyama, Y Luo, PM Hanno… - … Journal of Urology, 2020 - Wiley Online Library
Interstitial cystitis/bladder pain syndrome is a debilitating condition of unknown etiology
characterized by persistent pelvic pain with lower urinary tract symptoms and comprises a …

Mechanisms underlying overactive bladder and interstitial cystitis/painful bladder syndrome

L Grundy, A Caldwell, SM Brierley - Frontiers in neuroscience, 2018 - frontiersin.org
The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

Chronic psychological stress and lower urinary tract symptoms

R Chess‐Williams, C McDermott… - LUTS: Lower Urinary …, 2021 - Wiley Online Library
It is well established that lower urinary tract symptoms (LUTS), particularly urinary urgency
and incontinence, cause stress and anxiety for patients. However, there is mounting …

Stress-induced chronic visceral pain of gastrointestinal origin

B Greenwood-Van Meerveld… - Frontiers in Systems …, 2017 - frontiersin.org
Visceral pain is generally poorly localized and characterized by hypersensitivity to a
stimulus such as organ distension. In concert with chronic visceral pain, there is a high …

[HTML][HTML] Animal modelling of interstitial cystitis/bladder pain syndrome

L Birder, KE Andersson - International neurourology journal, 2018 - ncbi.nlm.nih.gov
The etiology of interstitial cystitis/bladder pain syndrome (IC/BPS) remains elusive and may
involve multiple causes. To better understand its pathophysiology, many efforts have been …

Broaden horizons: The advancement of interstitial cystitis/bladder pain syndrome

J Li, X Yi, J Ai - International Journal of Molecular Sciences, 2022 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating disease that induces
mental stress, lower urinary symptoms, and pelvic pain, therefore resulting in a decline in …

The effect of chronic psychological stress on lower urinary tract function: an animal model perspective

Y Gao, LV Rodríguez - Frontiers in Physiology, 2022 - frontiersin.org
Chronic psychological stress can affect urinary function and exacerbate lower urinary tract
(LUT) dysfunction (LUTD), particularly in patients with overactive bladder (OAB) or interstitial …

Psychological/mental stress‐induced effects on urinary function: Possible brain molecules related to psychological/mental stress‐induced effects on urinary function

T Shimizu, S Shimizu, Y Higashi… - International Journal of …, 2021 - Wiley Online Library
Exposure to psychological/mental stress can affect urinary function, and lead to and
exacerbate lower urinary tract dysfunctions. There is increasing evidence showing stress …

Preclinical models of endometriosis and interstitial cystitis/bladder pain syndrome: an Innovative Medicines Initiative-PainCare initiative to improve their value for …

P Nunez-Badinez, B De Leo, A Laux-Biehlmann… - Pain, 2021 - journals.lww.com
Endometriosis (ENDO) and interstitial cystitis/bladder pain syndrome (IC/BPS) are chronic
pain conditions for which better treatments are urgently needed. Development of new …

Animal models of interstitial cystitis/bladder pain syndrome

C Tay, L Grundy - Frontiers in Physiology, 2023 - frontiersin.org
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic disorder characterized by
pelvic and/or bladder pain, along with lower urinary tract symptoms that have a significant …