Objective High cerebral arterial pulsatility index (PI), white matter lesions (WMLs), enlarged
perivascular spaces (PVSs), and lacunar infarcts are common findings in the elderly …

Cognitive functions are well-preserved for some older individuals, but the underlying brain
mechanisms remain disputed. Here, 5-year longitudinal 3-back in-scanner and offline data …

Hypotension is a leading cause of age-related cognitive impairment. The available literature
evidences that vascular factors are associated with dementia and that hypotension alters …

Blood–brain barrier (BBB) disruption may contribute to cognitive decline, but questions
remain whether this association is more pronounced for certain brain regions, such as the …

介绍了超声成像技术与经颅超声治疗技术的优点, 综述了超声技术在重度抑郁症, 强迫症,
阿尔茨海默病, 精神分裂症以及其他精神疾病诊断, 治疗中的应用现状, 分析了超声技术在精神 …

Longitudinal research methods have brought the idea of change over time into social
science research, but time itself is often paid little attention in the construction of analytical …

The social sciences seek to understand the human experience. This experience unfolds
across time, so it is important for the social sciences to examine longitudinal data (Baltes & …

4D flow MRI is increasingly recognized as a highly versatile tool for deriving arterial and
venous hemodynamic information in studies on aging, dementia, and cerebrovascular …

Small vessel disease (SVD) is associated with elevated vascular stiffness and pulsatility, but
longitudinal studies are lacking. Using a 4D flow MRI approach sensitive to age-differences …