West syndrome: a comprehensive review

P Pavone, A Polizzi, SD Marino, G Corsello… - Neurological …, 2020 - Springer
Since its first clinical description (on his son) by William James West (1793–1848) in 1841,
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …

Infantile spasms: outcome in clinical studies

R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …

Efficacy and tolerability of the ketogenic diet versus high‐dose adrenocorticotropic hormone for infantile spasms: a single‐center parallel‐cohort randomized …

A Dressler, F Benninger, P Trimmel‐Schwahofer… - …, 2019 - Wiley Online Library
Objective To compare the efficacy and safety of the ketogenic diet (KD) with standard
adrenocorticotropic hormone (ACTH) treatment in infants with West syndrome. Methods In …

Antiepileptic drug treatment of epilepsy in children

ANV Moosa - CONTINUUM: Lifelong Learning in Neurology, 2019 - journals.lww.com
PURPOSE OF REVIEW The treatment of epilepsy in children is highly individualized at each
and every major step in the management. This review examines various factors that modify …

Design and implementation of electronic health record common data elements for pediatric epilepsy: Foundations for a learning health care system

ZM Grinspan, AD Patel, RA Shellhaas, AT Berg… - …, 2021 - Wiley Online Library
Abstract Objective Common data elements (CDEs) are standardized questions and answer
choices that allow aggregation, analysis, and comparison of observations from multiple …

The impact of hypsarrhythmia on infantile spasms treatment response: observational cohort study from the National Infantile Spasms Consortium

ST Demarest, RA Shellhaas, WD Gaillard, C Keator… - …, 2017 - Wiley Online Library
Summary Objective The multicenter National Infantile Spasms Consortium prospective
cohort was used to compare outcomes and phenotypic features of patients with infantile …

Treatment of infantile spasms

SA Hussain - Epilepsia open, 2018 - Wiley Online Library
The treatment of infantile spasms is challenging, especially in the context of the following:(1)
a severe phenotype with high morbidity and mortality;(2) the urgency of diagnosis and …

Infantile spasms of unknown cause: predictors of outcome and genotype-phenotype correlation

CJ Yuskaitis, MRZ Ruzhnikov, KB Howell, IE Allen… - Pediatric …, 2018 - Elsevier
ABSTRACT BACKGROUND No large-scale studies have specifically evaluated the
outcomes of infantile spasms (IS) of unknown cause, previously known as cryptogenic or …

Automatic detection of interictal ripples on scalp EEG to evaluate the effect and prognosis of ACTH therapy in patients with infantile spasms

W Wang, H Li, J Yan, H Zhang, X Li, S Zheng… - …, 2021 - Wiley Online Library
Objective We aimed to explore the feasibility of using scalp‐recorded high‐frequency
oscillations (HFOs) to evaluate the efficacy and prognosis of adrenocorticotropic hormone …

Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome

S Bhanudeep, P Madaan, N Sankhyan, L Saini… - Epilepsy Research, 2021 - Elsevier
Purpose To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes
and their predictors in a follow-up cohort with West syndrome (WS) at≥ 5 years of age …