Cyclodextrin multicomponent complexes: Pharmaceutical applications

V Aiassa, C Garnero, MR Longhi, A Zoppi - Pharmaceutics, 2021 - mdpi.com
Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely
used as carriers in the pharmaceutical industry for their ability to modulate several properties …

Current trends in molecular modeling methods applied to the study of cyclodextrin complexes

MA Quevedo, A Zoppi - Journal of Inclusion Phenomena and Macrocyclic …, 2018 - Springer
In this review the authors present an overview of different molecular modeling campaigns
dealing with the study and characterization of cyclodextrins (CDs) inclusion complexes with …

Amino acid chiral ionic liquids combined with hydroxypropyl-β-cyclodextrin for drug enantioseparation by capillary electrophoresis

S Salido-Fortuna, M Greño, M Castro-Puyana… - … of Chromatography A, 2019 - Elsevier
Four amino acid chiral ionic liquids were evaluated in dual systems with hydroxypropyl-β-
cyclodextrin to investigate the enantioseparation by CE of a group of seven drugs as model …

Formulation of piperine ternary inclusion complex using β CD and HPMC: physicochemical characterization, molecular docking, and antimicrobial testing

S Alshehri, SS Imam, A Hussain, MA Altamimi - Processes, 2020 - mdpi.com
The present study was designed to evaluate the effect of hydroxyl propyl methyl cellulose
(HPMC) on the complexation efficiency and dissolution of piperine (PPR) and β cyclodextrin …

Formulation and evaluation of supramolecular food-grade piperine HP β CD and TPGS complex: dissolution, physicochemical characterization, molecular docking, in …

SS Imam, S Alshehri, TA Alzahrani, A Hussain… - Molecules, 2020 - mdpi.com
The purpose of the present study was to improve the aqueous solubility, dissolution, and
antioxidant activity of the water-insoluble drug piperine (PIP). The study was performed by …

Enantiomeric separation of ivabradine by cyclodextrin-electrokinetic chromatography. Effect of amino acid chiral ionic liquids

N Casado, A Salgado, M Castro-Puyana… - … of Chromatography A, 2019 - Elsevier
A chiral methodology was developed for the first time to ensure the quality control of
ivabradine, a novel anti-ischemic and heart rate lowering drug commercialized as a pure …

Host-guest complex of β-cyclodextrin and pluronic F127 with Luteolin: Physicochemical characterization, anti-oxidant activity and molecular modeling studies

S Alshehri, SS Imam, MA Altamimi, M Jafar… - Journal of Drug Delivery …, 2020 - Elsevier
The purpose of this investigation was to ameliorate the solubility and dissolution rate of
luteolin (LUT) in aqueous phase by LUT: β-cyclodextrin (β CD) binary and LUT: β …

Capillary electrophoresis separation of phenethylamine enantiomers using amino acid based ionic liquids

J Wahl, U Holzgrabe - Journal of pharmaceutical and biomedical analysis, 2018 - Elsevier
In recent years increasing interest was drawn towards ionic liquids in analytical separation
science, such as capillary electrophoresis. Ionic liquids combining tetrabutylammonium …

[HTML][HTML] Formulation of multicomponent inclusion complex of cyclodextrin-amino acid with Chrysin: Physicochemical characterization, cell viability and apoptosis …

WA Mahdi, MM Alanazi, SS Imam, S Alshehri… - International Journal of …, 2023 - Elsevier
Chrysin (CR) is a water-insoluble drug reported for different therapeutic effects. The
microwave irradiation method was used in this study to create a multicomponent inclusion …

Enantiomeric determination of econazole and sulconazole by electrokinetic chromatography using hydroxypropyl-β-cyclodextrin combined with ionic liquids based on …

S Salido-Fortuna, ML Marina… - Journal of Chromatography …, 2020 - Elsevier
Two analytical methodologies based on the combined use of hydroxypropyl-β-cyclodextrin
and two different amino acid-based chiral ionic liquids (tetrabutylammonium-L-lysine or …