The role of TREX in gene expression and disease

CG Heath, N Viphakone, SA Wilson - Biochemical Journal, 2016 - portlandpress.com
TRanscription and EXport (TREX) is a conserved multisubunit complex essential for
embryogenesis, organogenesis and cellular differentiation throughout life. By linking …

Linking gene regulation to mRNA production and export

S Rodríguez-Navarro, E Hurt - Current opinion in cell biology, 2011 - Elsevier
Regulation of gene expression can occur at many different levels. One important step in the
gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In …

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

JJ Ipsaro, AD Haase, SR Knott, L Joshua-Tor… - Nature, 2012 - nature.com
PIWI-family proteins and their associated small RNAs (piRNAs) act in an evolutionarily
conserved innate immune mechanism to provide essential protection for germ-cell genomes …

Ehd4 Encodes a Novel and Oryza-Genus-Specific Regulator of Photoperiodic Flowering in Rice

H Gao, XM Zheng, G Fei, J Chen, M Jin, Y Ren… - PLoS …, 2013 - journals.plos.org
Land plants have evolved increasingly complex regulatory modes of their flowering time (or
heading date in crops). Rice (Oryza sativa L.) is a short-day plant that flowers more rapidly in …

CCCH-type zinc finger family in maize: genome-wide identification, classification and expression profiling under abscisic acid and drought treatments

X Peng, Y Zhao, J Cao, W Zhang, H Jiang, X Li, Q Ma… - PloS one, 2012 - journals.plos.org
Background CCCH-type zinc finger proteins comprise a large protein family. Increasing
evidence suggests that members of this family are RNA-binding proteins with regulatory …

Integrated multi-omics analysis of zinc-finger proteins uncovers roles in RNA regulation

ML Gosztyla, L Zhan, S Olson, X Wei, J Naritomi… - Molecular cell, 2024 - cell.com
RNA interactome studies have revealed that hundreds of zinc-finger proteins (ZFPs) are
candidate RNA-binding proteins (RBPs), yet their RNA substrates and functional …

A CCCH-type zinc finger nucleic acid-binding protein quantitatively confers resistance against rice bacterial blight disease

H Deng, H Liu, X Li, J Xiao, S Wang - Plant Physiology, 2012 - academic.oup.com
Bacterial blight is a devastating disease of rice (Oryza sativa) caused by Xanthomonas
oryzae pv oryzae (Xoo). Zinc finger proteins harboring the motif with three conserved …

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay

T Silla, M Schmid, Y Dou, W Garland… - Nucleic acids …, 2020 - academic.oup.com
Recruitment of the human ribonucleolytic RNA exosome to nuclear polyadenylated (pA+)
RNA is facilitated by the Poly (A) Tail eXosome Targeting (PAXT) connection. Besides its …

The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome

Y Zhou, J Zhu, G Schermann, C Ohle, K Bendrin… - Nature …, 2015 - nature.com
Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. However,
the mechanism by which they are recognized and targeted to the exosome is not fully …

The Arabidopsis tandem zinc finger 9 protein binds RNA and mediates pathogen-associated molecular pattern-triggered immune responses

LD Maldonado-Bonilla, L Eschen-Lippold… - Plant and Cell …, 2014 - academic.oup.com
Recognition of pathogen-associated molecular patterns (PAMPs) induces multiple defense
mechanisms to limit pathogen growth. Here, we show that the Arabidopsis thaliana tandem …