Advances in cardiac pacing: arrhythmia prediction, prevention and control strategies

MH Patel, S Sampath, A Kapoor, DN Damani… - Frontiers in …, 2021 - frontiersin.org
Cardiac arrhythmias constitute a tremendous burden on healthcare and are the leading
cause of mortality worldwide. An alarming number of people have been reported to manifest …

Reconstructing weighted networks from dynamics

ESC Ching, PY Lai, CY Leung - Physical Review E, 2015 - APS
We present a method that reconstructs both the links and their relative coupling strength of
bidirectional weighted networks. Our method requires only measurements of node dynamics …

Reconstructing network topology and coupling strengths in directed networks of discrete-time dynamics

PY Lai - Physical Review E, 2017 - APS
Reconstructing network connection topology and interaction strengths solely from
measurement of the dynamics of the nodes is a challenging inverse problem of broad …

[图书][B] Patterns in excitable media: Genesis, dynamics, and control

S Sinha, S Sridhar - 2014 - books.google.com
Excitable media comprise a class of models for a wide range of physical, chemical, and
biological systems that exhibit spontaneous formation of spatial patterns. Patterns in …

Control of cardiac alternans by mechanical and electrical feedback

F Yapari, D Deshpande, Y Belhamadia, S Dubljevic - Physical Review E, 2014 - APS
A persistent alternation in the cardiac action potential duration has been linked to the onset
of ventricular arrhythmia, which may lead to sudden cardiac death. A coupling between …

Dynamics study of constant diastolic interval and constant TR control for cardiac alternans based on a two-dimensional cellular automata model

M Xiong, K Sun, X Su, EG Tolkacheva, X Zhao - Nonlinear Dynamics, 2022 - Springer
As a precursor for cardiac arrhythmias such as atrial and ventricular fibrillations, which could
cause sudden cardiac death, cardiac alternans is essentially an unstable heart rhythm with …

Ionic characteristics in cardiac alternans suppression using T±ϵ feedback control

SN Liang, DM Le, PY Lai, CK Chan - Europhysics Letters, 2016 - iopscience.iop.org
Abstract Using the Luo-Rudy I model, the recently proposed $ T\pm\epsilon $ feedback
control for suppressing cardiac alternans is investigated. It is shown that cardiac alternans …

Control of electrical and calcium alternans in a one-dimensional cardiac cable

J Keong, BL Lan, E Lim, DM Le, SN Liang - Asia Simulation Conference, 2023 - Springer
Cardiac alternans is a beat-to-beat alternation in the electrical properties of the heart, such
as membrane potential and intracellular calcium (Ca) cycling in myocytes. Due to the bi …

Predicting self-terminating ventricular fibrillations in an isolated heart

DM Le, AV Dvornikov, PY Lai, CK Chan - Europhysics Letters, 2013 - iopscience.iop.org
Ventricular fibrillations (VFs) in isolated hearts induced by fast pacing are studied in a
Langendorff preparation by measuring the electrical signals from the right atrium $(V_a) …

Cardiac Alternans Suppression Under Feedback Control: Nonlinear Dynamics Analysis

SN Liang, DM Le, PY Lai - International Journal of Bifurcation and …, 2019 - World Scientific
The nonlinear dynamical properties of the recently proposed T±𝜖 feedback control for
suppressing cardiac alternans is investigated in detail for the discrete cardiac restitution map …