Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …

Organoids are in vitro cultures of miniature fetal or adult organ-like structures. Their
potentials for use in tissue and organ replacement, disease modeling, toxicology studies …

Following the sequencing of the human genome and many other organisms, research on
protein-coding genes and their functions (functional genomics) has intensified …

This article presents an overview of the literature and a review of recent advances in the
analysis of stable and transient protein–protein interactions (PPI s) with a focus on their …

Autism spectrum disorder (ASD) prevalence is increasing, with current estimates at 1/68–
1/50 individuals diagnosed with an ASD. Diagnosis is based on behavioral assessments …

Secretome analysis faces several challenges including detection of low abundant proteins
and the discrimination of bona fide secreted proteins from false-positive identifications …

Mass spectrometry (MS)-based proteomics has developed into a battery of approaches that
is exceedingly adept at identifying with high mass accuracy and precision any of the …

There are only 30,000 human genes, which, according to the central dogma from biology, it
means that there should be 30,000 mRNA and 30,000 proteins. However, there are at least …

To identify cancer-related proteins, we used isobaric tags in a relative and absolute
quantitation (iTRAQ) proteomic approach and SWATH™ quantification approach to analyze …

The secretome includes all macromolecules secreted by cells, in particular conditions at
defined times, allowing cell–cell communication. Cancer cell secretomes that are altered …