Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

Stroke is a leading cause of the adult disability epidemic in the United States, with a major
contribution from poststroke cognitive impairment and dementia (PSCID), the rates of which …

Cerebral small vessel disease (cSVD) is the most common cause of vascular cognitive
impairment and affects all levels of the brain's vasculature. Features include diverse …

For decades, the hypothesis that brain deposition of the amyloid β protein initiates
Alzheimer's disease has dominated research and clinical trials. Targeting amyloid β is …

Background In psychotic and mood disorders, immune alterations are hypothesized to
underlie cognitive symptoms, as they have been associated with elevated blood levels of …

The concept of vascular contributions to cognitive impairment and dementia (VCID) derives
from more than two decades of research indicating that (1) most older individuals with …

Background and purpose Although inflammation has been proposed to be a candidate risk
factor for cerebral small vessel disease (CSVD), previous findings remain largely …

Introduction To describe the protocol and findings of the instrumental validation of three
imaging‐based biomarker kits selected by the MarkVCID consortium: free water (FW) and …

INTRODUCTION High‐performing biomarkers measuring the vascular contributions to
cognitive impairment and dementia are lacking. METHODS Using a multi‐site observational …