Therapeutic effects of coumarins with different substitution patterns

V Flores-Morales, AP Villasana-Ruíz, I Garza-Veloz… - Molecules, 2023 - mdpi.com
The use of derivatives of natural and synthetic origin has gained attention because of their
therapeutic effects against human diseases. Coumarins are one of the most common …

Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis

MS Singh, S Chowdhury - Rsc Advances, 2012 - pubs.rsc.org
Multicomponent reactions have gained significant importance as a tool for the synthesis of a
wide variety of useful compounds, including pharmaceuticals. In this context, the multiple …

Coumarins: old compounds with novel promising therapeutic perspectives

ME Riveiro, N De Kimpe, A Moglioni… - Current medicinal …, 2010 - ingentaconnect.com
Natural as well as synthetic coumarins have recently drawn much attention due to its broad
pharmacological activities. Many coumarins and their derivatives exert anti-coagulant, anti …

Synthetic and natural coumarins as cytotoxic agents

I Kostova - Current Medicinal Chemistry-Anti-Cancer Agents, 2005 - ingentaconnect.com
Coumarins, an old class of compounds, are naturally occurring benzopyrene derivatives. A
lot of coumarins have been identified from natural sources, especially green plants. The …

[图书][B] Anticancer agents from natural products

GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

Seven metal-based bi-dentate NO azocoumarine complexes: Synthesis, physicochemical properties, DFT calculations, drug-likeness, in vitro antimicrobial screening …

A Abdou, HM Mostafa, AMM Abdel-Mawgoud - Inorganica Chimica Acta, 2022 - Elsevier
Abstract Herein, new Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Cu (II) and Zn (II) complexes based
on azocoumarin ligand, 2-[(E)-(2-oxo-2H-chromen-6-yl) diazenyl]-1-phenylbutane-1, 3 …

The structure and pharmacological functions of coumarins and their derivatives

L Wu, X Wang, W Xu, F Farzaneh… - Current medicinal …, 2009 - ingentaconnect.com
Coumarins are of many different structures. They constitute an important class of
pharmacological agents possessing a range of different physiological activities including …

Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies

C Ballatore, KR Brunden, DM Huryn, JQ Trojanowski… - 2012 - ACS Publications
The microtubule (MT) associated protein tau, which is highly expressed in the axons of
neurons, is an endogenous MT-stabilizing agent that plays an important role in axonal …

Anticancer drugs from nature—natural products as a unique source of new microtubule-stabilizing agents

KH Altmann, J Gertsch - Natural product reports, 2007 - pubs.rsc.org
Covering: up to June 2006This review article provides an overview on the current state of
research in the area of microtubule-stabilizing agents from natural sources, with a primary …

Recent advances and therapeutic journey of coumarins: current status and perspectives

KP Barot, SV Jain, L Kremer, S Singh… - Medicinal Chemistry …, 2015 - Springer
Coumarins are oxygen-containing molecules with specific benzopyrone nucleus. Different
coumarins are identified as antineurodegeneratives, anticoagulants, antioxidants …