Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice

M Westerterp, AJ Murphy, MI Wang, TA Pagler… - Circulation …, 2013 - Am Heart Assoc
Rationale: Plasma high-density lipoprotein levels are inversely correlated with
atherosclerosis. Although it is widely assumed that this is attributable to the ability of high …

High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target

TF Lüscher, U Landmesser, A von Eckardstein… - Circulation …, 2014 - Am Heart Assoc
High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …

Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation

I Gerin, LA Clerbaux, O Haumont, N Lanthier… - Journal of Biological …, 2010 - ASBMB
The regulation of synthesis, degradation, and distribution of lipids is crucial for homeostasis
of organisms and cells. The sterol regulatory element-binding protein (SREBP) transcription …

High-density lipoprotein heterogeneity and function in reverse cholesterol transport

GH Rothblat, MC Phillips - Current opinion in lipidology, 2010 - journals.lww.com
High-density lipoprotein heterogeneity and function in rever... : Current Opinion in Lipidology
High-density lipoprotein heterogeneity and function in reverse cholesterol transport : Current …

ATP-binding cassette transporters, atherosclerosis, and inflammation

M Westerterp, AE Bochem, L Yvan-Charvet… - Circulation …, 2014 - Am Heart Assoc
Although recent genome-wide association studies have called into question the causal
relationship between high-density lipoprotein (HDL) cholesterol levels and cardiovascular …

Bioactive egg components and inflammation

CJ Andersen - Nutrients, 2015 - mdpi.com
Inflammation is a normal acute response of the immune system to pathogens and tissue
injury. However, chronic inflammation is known to play a significant role in the …

The macrophage cholesterol exporter ABCA1 functions as an anti-inflammatory receptor

C Tang, Y Liu, PS Kessler, AM Vaughan… - Journal of Biological …, 2009 - ASBMB
ATP-binding cassette transporter A1 (ABCA1) is a cell membrane protein that exports
excess cholesterol from cells to apolipoprotein (apo) AI, the major protein in high density …

MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE−/− Mice

T Horie, O Baba, Y Kuwabara, Y Chujo… - Journal of the …, 2012 - Am Heart Assoc
Background Cholesterol efflux from cells to apolipoprotein A‐I (apoA‐I) acceptors via the
ATP‐binding cassette transporters ABCA 1 and ABCG 1 is thought to be central in the …