Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

The biological and social phenomenon of Lyme disease

AG Barbour, D Fish - Science, 1993 - science.org
Lyme disease, unknown in the United States two decades ago, is now the most common
arthropod-borne disease in the country and has caused considerable morbidity in several …

Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins

B Henderson, S Nair, J Pallas… - FEMS microbiology …, 2011 - academic.oup.com
Fibronectin, a large and essential multidomain glycoprotein, with multiple adhesive
properties, functioning as a key link between cells and their extracellular matrices, is now …

The pathogenesis of lyme neuroborreliosis: from infection to inflammation

TA Rupprecht, U Koedel, V Fingerle, HW Pfister - Molecular medicine, 2008 - Springer
This review describes the current knowledge of the pathogenesis of acute Lyme
neuroborreliosis (LNB), from invasion to inflammation of the central nervous system. Borrelia …

Identification of a 47 kDa fibronectin‐binding protein expressed by Borrelia burgdorferi isolate B31

WS Probert, BJB Johnson - Molecular microbiology, 1998 - Wiley Online Library
The attachment of pathogenic microorganisms to host cells and tissues is often mediated
through the expression of surface receptors recognizing components of the extracellular …

The role of Borrelia burgdorferi outer surface proteins

MR Kenedy, TR Lenhart… - FEMS Immunology & …, 2012 - academic.oup.com
Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …

Role of fibronectin-binding MSCRAMMs in bacterial adherence and entry into mammalian cells

D Joh, ER Wann, B Kreikemeyer, P Speziale, M Höök - Matrix Biology, 1999 - Elsevier
Most bacterial infections are initiated by the adherence of microorganisms to host tissues.
This process involves the interaction of specific bacterial surface structures, called adhesins …

Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host

TJ Moriarty, MU Norman, P Colarusso… - PLoS …, 2008 - journals.plos.org
Pathogenic spirochetes are bacteria that cause a number of emerging and re-emerging
diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme borreliosis …

Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks

SM Dunham-Ems, MJ Caimano, U Pal… - The Journal of …, 2009 - Am Soc Clin Investig
Lyme disease is caused by transmission of the spirochete Borrelia burgdorferi from ticks to
humans. Although much is known about B. burgdorferi replication, the routes and …

Detection of Borrelia burgdorferi in patients with Lyme disease by the polymerase chain reaction.

EC Guy, G Stanek - Journal of clinical pathology, 1991 - jcp.bmj.com
Borrelia burgdorferi, the causative agent of Lyme disease, was detected in patients' serum
by DNA amplification using the polymerase chain reaction (PCR). B burgdorferi was pelleted …