Iron is critical for the appearance and maintenance of life on Earth. Almost all organisms
compete or cooperate for iron acquisition, demonstrating the importance of this essential …

Metformin (dimethyl biguanide) is a synthetic derivative of guanidine, isolated from the
extracts of Galega officinalis, a plant with a prominent antidiabetic effect. Since its discovery …

Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Immune dysfunction is widely regarded as one of the central tenants underpinning the
pathophysiology of diabetes mellitus (DM) and its complications. When discussing immunity …

Youth-onset Type 2 Diabetes Mellitus (T2DM) represents a major burden worldwide. In the
last decades, the prevalence of T2DM became higher than that of Type 1 Diabetes Mellitus …

In this study, we demonstrate a novel affinity peptide-incorporated electrochemical
biosensor for the detection of acute kidney injury and the diabetic biomarker neutrophil …

Grifola frondosa is an edible fungus with a variety of potential pharmacological activities.
This study investigates the hypoglycemic, anti-diabetic nephritic, and antioxidant properties …

Background Insulin impairment and inflammation are two features common to type 2
diabetes and Alzheimer's disease; however, the molecular and signaling interactions …

Doxorubicin (DOX) is a frequent chemotherapeutic drug used to treat various malignant
tumors. One of the key factors that diminish its therapeutic importance is DOX-induced …

Recent trials based on surrogate outcome measures have provided further data suggesting
protective effects of metformin against vascular disease in youth and adults with Type 1 …