Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …

Myriad biological processes proceed through states that defy characterization by
conventional atomic-resolution structural biological methods. The invisibility of these …

Quantitative studies in molecular and structural biology generally require accurate and
precise determination of protein concentrations, preferably via a method that is both quick …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

The importance of dynamics to biomolecular function is becoming increasingly clear. A
description of the structure–function relationship must, therefore, include the role of motion …

Recent advances in rapid mixing and freeze quenching have opened the path for time-
resolved electron paramagnetic resonance (EPR)-based double electron-electron …

Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human
diseases. Recent advances in electron microscopy and solid state NMR have allowed the …

Paramagnetic NMR data contain extremely accurate long-range information on
metalloprotein structures and, when used in the frame of integrative structural biology …

Abstract The Ca 2+-sensing receptor (CaSR) regulates the calcium homeostasis in the
human body via sensing fluctuations in the extracellular Ca 2+ concentration. Naturally …

Direct structural and dynamic characterization of protein conformers in solution is highly
desirable but currently impractical. Herein, we developed a single molecule gold plasmonic …