The role of the VEGF family in coronary heart disease

Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

The leading role of epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis

M Selman, A Pardo - Cellular signalling, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …

The role of the VEGF family in atherosclerosis development and its potential as treatment targets

SA Dabravolski, VA Khotina, AV Omelchenko… - International journal of …, 2022 - mdpi.com
The vascular endothelial growth factor (VEGF) family, the crucial regulator of angiogenesis,
lymphangiogenesis, lipid metabolism and inflammation, is involved in the development of …

TGF‑β1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis

Z Ye, Y Hu - International journal of molecular …, 2021 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is a worldwide disease characterized by the chronic and
irreversible decline of lung function. Currently, there is no drug to successfully treat the …

TGF-β signaling: critical nexus of fibrogenesis and cancer

AO Giarratana, CM Prendergast, MM Salvatore… - Journal of Translational …, 2024 - Springer
The transforming growth factor-beta (TGF-β) signaling pathway is a vital regulator of cell
proliferation, differentiation, apoptosis, and extracellular matrix production. It functions …

Palmitic acid–rich high-fat diet exacerbates experimental pulmonary fibrosis by modulating endoplasmic reticulum stress

SG Chu, JA Villalba, X Liang, K Xiong… - American Journal of …, 2019 - atsjournals.org
The impact of lipotoxicity on the development of lung fibrosis is unclear. Saturated fatty
acids, such as palmitic acid (PA), activate endoplasmic reticulum (ER) stress, a cellular …

A combination of MTAP and BAP1 immunohistochemistry in pleural effusion cytology for the diagnosis of mesothelioma

Y Kinoshita, T Hida, M Hamasaki… - Cancer …, 2018 - Wiley Online Library
BACKGROUND Homozygous deletion of 9p21 detected by fluorescence in situ hybridization
(FISH) and loss of BRCA1‐associated protein 1 (BAP1) expression detected by …

Roles of the TGF-β–VEGF-C pathway in fibrosis-related lymphangiogenesis

H Kinashi, Y Ito, T Sun, T Katsuno, Y Takei - International journal of …, 2018 - mdpi.com
Lymphatic vessels drain excess tissue fluids to maintain the interstitial environment.
Lymphatic capillaries develop during the progression of tissue fibrosis in various clinical and …

TGF-β1-VEGF-A pathway induces neoangiogenesis with peritoneal fibrosis in patients undergoing peritoneal dialysis

T Kariya, H Nishimura, M Mizuno… - American Journal …, 2018 - journals.physiology.org
The characteristic features of chronic peritoneal injury with peritoneal dialysis (PD) are
submesothelial fibrosis and neoangiogenesis. Transforming growth factor (TGF) β and …

Emerging roles for VEGF-D in human disease

SA Stacker, MG Achen - Biomolecules, 2018 - mdpi.com
Blood vessels and lymphatic vessels are located in many tissues and organs throughout the
body, and play important roles in a wide variety of prevalent diseases in humans. Vascular …