Mouse anesthesia: the art and science

KL Navarro, M Huss, JC Smith, P Sharp, JO Marx… - ILAR …, 2021 - academic.oup.com
There is an art and science to performing mouse anesthesia, which is a significant
component to animal research. Frequently, anesthesia is one vital step of many over the …

The (un) conscious mouse as a model for human brain functions: key principles of anesthesia and their impact on translational neuroimaging

HM Reimann, T Niendorf - Frontiers in systems neuroscience, 2020 - frontiersin.org
In recent years, technical and procedural advances have brought functional magnetic
resonance imaging (fMRI) to the field of murine neuroscience. Due to its unique capacity to …

Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models

J Horder, MM Petrinovic, MA Mendez, A Bruns… - Translational …, 2018 - nature.com
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high
human and economic burden. The pathophysiology of ASD is largely unclear, thus …

Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1–induced mechanisms

Z Helyes, V Tékus, N Szentes… - Proceedings of the …, 2019 - National Acad Sciences
Neuroimmune interactions may contribute to severe pain and regional inflammatory and
autonomic signs in complex regional pain syndrome (CRPS), a posttraumatic pain disorder …

[HTML][HTML] Sensory evoked fMRI paradigms in awake mice

X Chen, C Tong, Z Han, K Zhang, B Bo, Y Feng… - Neuroimage, 2020 - Elsevier
Mouse fMRI has become increasingly popular in the small animal imaging field. However,
compared to the more commonly used rat fMRI, it is challenging for mouse fMRI to obtain …

[HTML][HTML] Characteristics of fMRI responses to visual stimulation in anesthetized vs. awake mice

TNA Dinh, WB Jung, HJ Shim, SG Kim - Neuroimage, 2021 - Elsevier
The functional characteristics of the mouse visual system have not previously been well
explored using fMRI. In this research, we examined 9.4 T BOLD fMRI responses to visual …

Awake and behaving mouse fMRI during Go/No-Go task

Z Han, W Chen, X Chen, K Zhang, C Tong, X Zhang… - Neuroimage, 2019 - Elsevier
Functional magnetic imaging (fMRI) has been widely used to examine the functional neural
networks in both the evoked and resting states. However, most fMRI studies in rodents are …

Mouse fMRI under ketamine and xylazine anesthesia: Robust contralateral somatosensory cortex activation in response to forepaw stimulation

HJ Shim, WB Jung, F Schlegel, J Lee, S Kim, J Lee… - Neuroimage, 2018 - Elsevier
Mouse fMRI is critically useful to investigate functions of mouse models. Until now, the
somatosensory-evoked responses in anesthetized mice are often widespread and …

Characterization of brain-wide somatosensory BOLD fMRI in mice under dexmedetomidine/isoflurane and ketamine/xylazine

T You, GH Im, SG Kim - Scientific reports, 2021 - nature.com
Mouse fMRI under anesthesia has become increasingly popular due to improvement in
obtaining brain-wide BOLD response. Medetomidine with isoflurane has become well …

Male and female C57BL/6 mice respond differently to awake magnetic resonance imaging habituation

TB Lindhardt, E Gutiérrez-Jiménez, Z Liang… - Frontiers in …, 2022 - frontiersin.org
Traditionally, preclinical magnetic resonance imaging (MRI) has been performed in
anesthetized animals. However, anesthesia has been shown to perturb normal brain …