[HTML][HTML] Extracellular Matrix Components and Mechanosensing Pathways in Health and Disease

A Berdiaki, M Neagu, P Tzanakakis, I Spyridaki… - Biomolecules, 2024 - mdpi.com
Glycosaminoglycans (GAGs) and proteoglycans (PGs) are essential components of the
extracellular matrix (ECM) with pivotal roles in cellular mechanosensing pathways. GAGs …

Spontaneous orthogonal alignment of smooth muscle cells and endothelial cells captures native blood vessel morphology in tissue-engineered vascular grafts

H Alkazemi, T Huang, M Mail… - … Applied Materials & …, 2023 - ACS Publications
Tissue-engineered vascular grafts (TEVGs) have emerged as a potential alternative to
autologous grafts for replacing small-diameter blood vessels during bypass surgery. The …

REDV-Functionalized Recombinant Spider Silk for Next-Generation Coronary Artery Stent Coatings: Hemocompatible, Drug-Eluting, and Endothelial Cell-Specific …

K Mayer, A Ruhoff, NJ Chan… - … Applied Materials & …, 2024 - ACS Publications
Coronary artery stents are life-saving devices, and millions of these devices are implanted
annually to treat coronary heart disease. The current gold standard in treatment is drug …

Engineering Nanoclusters of Cell Adhesive Ligands on Biomaterial Surfaces: Superior Cell Proliferation and Myotube Formation for Skeletal Muscle Tissue …

S Nour, S Shabani, K Swiderski… - Advanced …, 2025 - Wiley Online Library
Engineering biointerfaces with nanoscale clustering of integrin‐binding cell adhesive
peptides is critical for promoting receptor redistribution into signaling complexes. Skeletal …

[PDF][PDF] Vascular Microphysiological System for Investigating Endothelial Barrier Function during Organ Preservation and Reperfusion

Y Kim, I Goswami, E Gill, SR Mahmoodi… - …, 2024 - assets-eu.researchsquare.com
Endothelial cell damage after cold preservation and reperfusion injury causes deterioration
of the endothelial barrier and ultimately results in edema, leading to transplant failure. Here …

Emerging biomaterials and technologies to control stem cell fate and patterning in engineered 3D tissues and organoids

M Farahani, J Carthew, S Bhowmik, C Shard… - …, 2022 - pubs.aip.org
The ability to create complex three-dimensional cellular models that can effectively replicate
the structure and function of human organs and tissues in vitro has the potential to …

Syndecan-4 promotes vascular beds formation in tissue engineered liver via thrombospondin 1

X Hu, J Chen, H Huang, S Yin, S Zheng, L Zhou - Bioengineered, 2020 - Taylor & Francis
Instantaneous blood coagulation after bioengineered liver transplantation is a major issue,
and the key process in its prevention is the construction of the endothelial vascular bed on …

Identification of circulating cells interacted with integrin α4β1 ligand peptides REDV or HGGVRLY

YI Hsu, A Mahara, T Yamaoka - Peptides, 2021 - Elsevier
Recently, artificial blood vessels modified by integrin α4β1 ligand, such as REDV, showed
endothelialization improvement and antithrombotic properties have been reported. Early …

Vascular Microphysiological System for Investigating Endothelial Barrier Function during Organ Preservation and Reperfusion

K Healy, Y Kim, I Goswami, E Gill, SR Mahmoodi… - 2024 - researchsquare.com
Endothelial cell damage after cold preservation and reperfusion injury causes deterioration
of the endothelial barrier and ultimately results in edema, leading to transplant failure. Here …

Engineered Biomimetic platforms to analyse molecular and cellular role of Heparan Sulfate on BMP2 bioactivity

J Sefkow-Werner - 2021 - theses.hal.science
The extra cellular matrix (ECM) provides mechanical structure to embedded cells and gives
biochemical cues to regulate homeostasis and differentiation. The structural molecule …