Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Acinetobacter baumannii Resistance: A Real Challenge for Clinicians

R Vázquez-López, SG Solano-Gálvez… - Antibiotics, 2020 - mdpi.com
Acinetobacter baumannii (named in honor of the American bacteriologists Paul and Linda
Baumann) is a Gram-negative, multidrug-resistant (MDR) pathogen that causes nosocomial …

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies

Y Cai, D Chai, R Wang, B Liang… - Journal of antimicrobial …, 2012 - academic.oup.com
Colistin is the last resort for treatment of multidrug-resistant Acinetobacter baumannii.
Unfortunately, resistance to colistin has been reported all over the world. The highest …

[HTML][HTML] Systematic review and meta-analysis of in vitro efficacy of antibiotic combination therapy against carbapenem-resistant Gram-negative bacilli

L Scudeller, E Righi, M Chiamenti, D Bragantini… - International journal of …, 2021 - Elsevier
Background: The superiority of combination therapy for carbapenem-resistant Gram-
negative bacilli (CR-GNB) remains controversial. In vitro models may predict the efficacy of …

Systematic Review and Meta-Analysis of In Vitro Synergy of Polymyxins and Carbapenems

O Zusman, T Avni, L Leibovici, A Adler… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Our objective was to examine the evidence of in vitro synergy of polymyxin-carbapenem
combination therapy against Gram-negative bacteria (GNB). A systematic review and meta …

Combined effect of polymyxin B and tigecycline to overcome heteroresistance in carbapenem-resistant Klebsiella pneumoniae

Y Tian, QY Zhang, LR Wen, JS Chen - Microbiology spectrum, 2021 - Am Soc Microbiol
We assessed the prevalence of polymyxin B (PMB)-and tigecycline (TGC)-heteroresistant
Klebsiella pneumoniae isolates and investigated the combined effect of PMB and TGC …

Systematic Review of Antimicrobial Combination Options for Pandrug-Resistant Acinetobacter baumannii

S Karakonstantis, P Ioannou, G Samonis, DP Kofteridis - Antibiotics, 2021 - mdpi.com
Antimicrobial combinations are at the moment the only potential treatment option for
pandrug-resistant A. baumannii. A systematic review was conducted in PubMed and Scopus …

Isolation of extensively drug resistant Acinetobacter baumannii from environmental surfaces inside intensive care units

Q Ababneh, S Abulaila, Z Jaradat - American Journal of Infection Control, 2022 - Elsevier
Background Acinetobacter baumannii is a nosocomial pathogen that has emerged as a
major threat in the health-care settings, particularly intensive care units (ICUs). The aim of …

Synergistic antimicrobial activity between the broad spectrum bacteriocin garvicin KS and nisin, farnesol and polymyxin B against gram-positive and gram-negative …

H Chi, H Holo - Current microbiology, 2018 - Springer
The increasing emergence of antibiotics resistance is of global concern. Finding novel
antimicrobial agents and strategies based on synergistic combinations are essential to …