Type I interferons (IFN-Is) are important players in the immunopathogenesis of systemic
lupus erythematosus (SLE). Pathogenic events in patients with SLE are potent triggers of …

Abstract Purpose of Review Bone homeostasis is balanced between formation and
resorption activities and remain in relative equilibrium. Under disease states this process is …

Background T cell infiltration and differentiation play a central part in the development of
lupus nephritis (LN). Our prior research has indicated that protein, the primary active …

Objective This study aimed to compare the efficacy and safety of biologics, multitarget
therapy, and standard therapy for the induction of lupus nephritis. Methods A systematic …

Voclosporin is an oral CNI that binds cyclophilin A in T-cells.[2] The drug molecule has a
cyclic undecapeptide structure of 11 amino acids, originally isolated from a fungus species …

Background: In Switzerland, nephrologists must frequently obtain pre-authorizations from
health insurers for certain medications/tests for individual patients. These are time …

Estimado Editor, La nefritis lúpica (NL) es una de las manifestaciones más frecuentes del
lupus eritematoso sistémico (LES) y afecta aproximadamente al 40% de los pacientes. La …

Abstract Chronic Kidney Disease is reported as a “Kidney damage for≥ 3 months, as
defined by structural or functional abnormalities of the kidney, with or without decreased …

Die Lupusnephritis (LN) ist eine schwere und häufige Organmanifestation des systemischen
Lupus Erythematodes (SLE), die die Morbidität und Mortalität der Patient/-innen erheblich …

Objectives: Identify the signs and symptoms of LWE through careful patient assessment and
evaluation. Develop and implement appropriate treatment strategies and interventions …