The therapeutic effects and mechanisms of quercetin on metabolic diseases: pharmacological data and clinical evidence

H Yi, H Peng, X Wu, X Xu, T Kuang… - Oxidative medicine …, 2021 - Wiley Online Library
Metabolic diseases have become major public health issues worldwide. Searching for
effective drugs for treating metabolic diseases from natural compounds has attracted …

Quercetin and the mitochondria: a mechanistic view

MR de Oliveira, SM Nabavi, N Braidy, WN Setzer… - Biotechnology …, 2016 - Elsevier
Quercetin is an important flavonoid that is ubiquitously present in the diet in a variety of fruits
and vegetables. It has been traditionally viewed as a potent antioxidant and anti …

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related …

D Porras, E Nistal, S Martínez-Flórez… - Free Radical Biology …, 2017 - Elsevier
Gut microbiota is involved in obesity, metabolic syndrome and the progression of
nonalcoholic fatty liver disease (NAFLD). It has been recently suggested that the flavonoid …

Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice

H Yang, T Yang, C Heng, Y Zhou, Z Jiang… - Phytotherapy …, 2019 - Wiley Online Library
Multiphase pathological processes involve in Type 2 diabetes (T2DM)‐induced
nonalcoholic fatty liver disease (NAFLD). However, the therapies are quite limited. In the …

Polyphenols as potential metabolism mechanisms regulators in liver protection and liver cancer prevention

S Li, S Yin, H Ding, Y Shao, S Zhou, W Pu… - Cell …, 2023 - Wiley Online Library
Background Liver cancer is one of the common malignancies. The dysregulation of
metabolism is a driver of accelerated tumourigenesis. Metabolic changes are well …

Quercetin ameliorates HFD-induced NAFLD by promoting hepatic VLDL assembly and lipophagy via the IRE1a/XBP1s pathway

X Zhu, T Xiong, P Liu, X Guo, L Xiao, F Zhou… - Food and chemical …, 2018 - Elsevier
The consumption of a quercetin-rich diet has been well-established as a feasible method
against non-alcoholic fatty liver disease (NAFLD); however, the molecular mechanisms …

[HTML][HTML] Herbal medicines and nonalcoholic fatty liver disease

H Yao, YJ Qiao, YL Zhao, XF Tao, LN Xu… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD), which is characterized by excessive fat
accumulation in the liver of patients who consume little or no alcohol, becomes increasingly …

Starch-anthocyanins complex: characterization, digestibility, and mechanism

W Zhang, J Kong, M Zhang, Y Chen, Q Yu, M Shen… - Food …, 2024 - Elsevier
Starch, as a sustainable polymer, is the main source of energy for human beings. However,
natural starch usually has some disadvantages, such as unstable structure, and high …

Targeting heme oxygenase-1 by quercetin ameliorates alcohol-induced acute liver injury via inhibiting NLRP3 inflammasome activation

S Liu, L Tian, G Chai, B Wen, B Wang - Food & function, 2018 - pubs.rsc.org
Alcoholic hepatitis (AH) is characterized by inflammation and necrosis of liver tissue caused
by excessive alcohol consumption and it even causes organ failure sometimes, in which …

Intestinal microbiota modulation in obesity-related non-alcoholic fatty liver disease

D Porras, E Nistal, S Martínez-Flórez… - Frontiers in …, 2018 - frontiersin.org
Obesity and associated comorbidities, including non-alcoholic fatty liver disease (NAFLD),
are a major concern to public well-being worldwide due to their high prevalence among the …