Diagnosis and management of noncardiac complications in adults with congenital heart disease: a scientific statement from the American Heart Association
GK Lui, A Saidi, AB Bhatt, LJ Burchill, JF Deen… - Circulation, 2017 - Am Heart Assoc
Life expectancy and quality of life for those born with congenital heart disease (CHD) have
greatly improved over the past 3 decades. While representing a great advance for these …
greatly improved over the past 3 decades. While representing a great advance for these …
Fontan‐associated liver disease
MB Hilscher, ML Wells, SK Venkatesh, F Cetta… - …, 2022 - Wiley Online Library
Fontan-associated liver disease (FALD) is a form of congestive hepatopathy that is universal
among patients who have undergone Fontan palliation for functional single ventricle …
among patients who have undergone Fontan palliation for functional single ventricle …
Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism
Bile acids activate farnesoid X receptor (FXR) and G protein–coupled bile acid receptor‐1
(aka Takeda G protein–coupled receptor‐5 [TGR5]) to regulate bile acid metabolism and …
(aka Takeda G protein–coupled receptor‐5 [TGR5]) to regulate bile acid metabolism and …
The clinical spectrum of Fontan-associated liver disease: results from a prospective multimodality screening cohort
ID Munsterman, AL Duijnhouwer… - European heart …, 2019 - academic.oup.com
Aims Liver fibrosis and cirrhosis are a consequence of a Fontan physiology, and determine
prognosis. It is unclear whether non-invasive assessment of liver pathology is helpful to …
prognosis. It is unclear whether non-invasive assessment of liver pathology is helpful to …
[PDF][PDF] Assessment of advanced liver fibrosis and the risk for hepatic decompensation in patients with congestive hepatopathy
A Lemmer, LB VanWagner, D Ganger - Hepatology, 2018 - Wiley Online Library
Congestive hepatopathy (CH) arises from chronically elevated right‐sided heart pressures
transmitted to the liver by passive venous congestion. Over time, CH can lead to hepatic …
transmitted to the liver by passive venous congestion. Over time, CH can lead to hepatic …
Low‐dose interleukin‐2 for refractory autoimmune hepatitis
TY Lim, M Martinez‐Llordella, E Kodela, E Gray… - Hepatology, 2018 - journals.lww.com
Congestive hepatopathy (CH) arises from chronically elevated right‐sided heart pressures
transmitted to the liver by passive venous congestion. Over time, CH can lead to hepatic …
transmitted to the liver by passive venous congestion. Over time, CH can lead to hepatic …
Risk factors for Fontan-associated hepatocellular carcinoma
T Kogiso, T Sagawa, M Taniai, E Shimada, K Inai… - PLoS …, 2022 - journals.plos.org
Aims The incidence of hepatocellular carcinoma (HCC) in patients with Fontan-associated
liver disease (ie, FALD-HCC) has increased over time. However, the risk factors for HCC …
liver disease (ie, FALD-HCC) has increased over time. However, the risk factors for HCC …
Fontan-associated liver disease and hepatocellular carcinoma in adults
T Kogiso, K Tokushige - Scientific Reports, 2020 - nature.com
The Fontan operation creates a unique circulation, and is a palliative therapy for patients
with single-ventricle congenital heart disease. Increased venous pressure and decreased …
with single-ventricle congenital heart disease. Increased venous pressure and decreased …
[HTML][HTML] Noninvasive surrogates are poor predictors of liver fibrosis in patients with Fontan circulation
YR Shin, SU Kim, S Lee, JY Choi, HK Park… - The Journal of Thoracic …, 2022 - Elsevier
Abstract Objectives Patients with Fontan circulation exhibit a high incidence of liver fibrosis
and cirrhosis. Transient elastography (TE) and the enhanced liver fibrosis (ELF) test have …
and cirrhosis. Transient elastography (TE) and the enhanced liver fibrosis (ELF) test have …