HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus

EK Halvas, KW Joseph, LD Brandt… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND HIV-1 viremia that is not suppressed by combination antiretroviral therapy
(ART) is generally attributed to incomplete medication adherence and/or drug resistance …

Synthesis and characterization of long-acting Darunavir prodrugs

MG Banoub, AN Bade, Z Lin, D Cobb… - Molecular …, 2019 - ACS Publications
Antiretroviral therapy (ART) has improved the quality of life in patients infected with HIV-1.
However, complete viral suppression within anatomical compartments remains unattainable …

Clinical pharmacology profile of boceprevir, a hepatitis C virus NS3 protease inhibitor: focus on drug–drug interactions

S Khalilieh, HP Feng, EGJ Hulskotte… - Clinical …, 2015 - Springer
Boceprevir is a potent, orally administered ketoamide inhibitor that targets the active site of
the hepatitis C virus (HCV) non-structural (NS) 3 protease. The addition of boceprevir to …

[引用][C] Combined oral contraceptives as victims of drug interactions

L Li, X Yang, D Tran, SK Seo, Y Lu - Drug Metabolism and Disposition, 2023 - ASPET

Safely treating hepatitis C in patients with HIV or hepatitis B virus coinfection

A Jafari, H Khalili, M Izadpanah… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: There are several clinical trials and prospective studies which support the use
of direct-acting antiviral agents (DAAs) in hepatitis C virus (HCV)-coinfected patients. In this …

[引用][C] DRUG INTERACTIONS WITH DISCONTINUED HEPATITIS C PROTEASE INHIBITORS

BM US, HCV Squibb's - Vertex, 2014