Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking, molecular …
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
[HTML][HTML] Target specificity of selective bioactive compounds in blocking α-dystroglycan receptor to suppress Lassa virus infection: an in silico approach
Lassa hemorrhagic fever, caused by Lassa mammarenavirus (LASV) infection, accumulates
up to 5000 deaths every year. Currently, there is no vaccine available to combat this …
up to 5000 deaths every year. Currently, there is no vaccine available to combat this …
Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
[HTML][HTML] Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the …
Objective: Despite the development of several vaccines against severe acute respiratory
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
An in-silico identification of potential flavonoids against kidney fibrosis targeting TGFβR-1
Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic
cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and …
cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and …
[HTML][HTML] Catabolic profiling of selective enzymes in the saccharification of non-food lignocellulose parts of biomass into functional edible sugars and bioenergy: An in …
Objectives: The research aims to analyze the catabolic strength of different hydrolytic
enzymes in assessing the biological conversion potential of lignocellulose parts of …
enzymes in assessing the biological conversion potential of lignocellulose parts of …
Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings …
HCV is a hepatotropic RNA virus recognized for its frequent virulence and fatality worldwide.
Despite many vaccine development programs underway, researchers are on a quest for …
Despite many vaccine development programs underway, researchers are on a quest for …
[HTML][HTML] Active site-specific quantum tunneling of hACE2 receptor to assess its complexing poses with selective bioactive compounds in co-suppressing SARS-CoV-2 …
Objective: This research aims to study the target specificity of selective bioactive compounds
in complexing with the human angiotensin-converting enzyme (hACE2) receptor to impede …
in complexing with the human angiotensin-converting enzyme (hACE2) receptor to impede …
WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing …
The research aimed to establish a multidrug-resistant Klebsiella pneumoniae-induced
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …