DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

SOX2 is a well-characterized pluripotent factor that is essential for stem cell self-renewal,
reprogramming, and homeostasis. The cellular levels of SOX2 are precisely regulated by a …

Epithelial–mesenchymal transition (EMT) is an important process for cancer metastasis,
drug resistance, and cancer stem cells. Activation of fibroblast growth factor receptor 1 …

Cell identity is largely determined by its transcriptional profile. In tumour, deregulation of
transcription factor expression and/or activity enables cancer cell to acquire a stem-like state …

Increased understanding of intrinsically disordered proteins (IDPs) and protein regions has
revolutionized our view of the relationship between protein structure and function. Data now …

The pluripotency transcription factor SOX2 is essential for the maintenance of glioblastoma
stem cells (GSC), which are thought to underlie tumor growth, treatment resistance, and …

Glioblastoma (GBM) is the most common, most aggressive and deadliest brain tumor.
Recently, remarkable progress has been made towards understanding the cellular and …

Nucleic acids play crucial roles in transferring cellular information and gene regulations.
DNA and RNA molecules have been associated with multiple human diseases and thus …

Abstract Pyrrole–imidazole polyamides (Py–Im polyamides) are cell-permeable compounds
that bind to the minor groove of double-stranded DNA in a sequence-specific manner …

Recent innovations in cutting-edge sequencing platforms have allowed the rapid
identification of genes associated with communicable, noncommunicable and rare diseases …