[HTML][HTML] Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial …

P Tian, KJ O'Riordan, Y Lee, G Wang, J Zhao… - Neurobiology of …, 2020 - Elsevier
Background Accumulating evidence points to an association between gut microbial
abnormalities and depression disorder. The microbiota-gut-brain axis is an emerging target …

Novel aspects of enteric serotonergic signaling in health and brain-gut disease

A Del Colle, N Israelyan… - American Journal of …, 2020 - journals.physiology.org
Gastrointestinal (GI) comorbidities are common in individuals with mood and behavioral
dysfunction. Similarly, patients with GI problems more commonly suffer from co-morbid …

Effects of serotonin and slow-release 5-hydroxytryptophan on gastrointestinal motility in a mouse model of depression

N Israelyan, A Del Colle, Z Li, Y Park, A Xing… - Gastroenterology, 2019 - Elsevier
Background & Aims Mood disorders and constipation are often comorbid, yet their shared
etiologies have rarely been explored. The neurotransmitter serotonin (5-HT) regulates …

Association analysis of gut microbiota and efficacy of SSRIs antidepressants in patients with major depressive disorder

M Gao, H Tu, P Liu, Y Zhang, R Zhang, L Jing… - Journal of Affective …, 2023 - Elsevier
Background Relevant studies have shown that gut microbiome plays an important role in the
occurrence, development and treatment of major depressive disorder (MDD). Many studies …

Gut bacteria-derived 5-hydroxyindole is a potent stimulant of intestinal motility via its action on L-type calcium channels

B Waclawiková, A Bullock, M Schwalbe… - PLoS …, 2021 - journals.plos.org
Microbial conversion of dietary or drug substrates into small bioactive molecules represents
a regulatory mechanism by which the gut microbiota alters intestinal physiology. Here, we …

Oral administration of 5-hydroxytryptophan restores gut microbiota dysbiosis in a mouse model of depression

L Wu, L Ran, Y Wu, M Liang, J Zeng, F Ke… - Frontiers in …, 2022 - frontiersin.org
5-Hydroxytryptophan (5-HTP) has positive clinical effects on various neuropsychiatric and
metabiotic disorders, especially depression. Although it increases serotonin levels in the …

Gut microbiome and major depressive disorder: Insights from two-sample Mendelian randomization

Q Zhao, A Baranova, H Cao, F Zhang - BMC psychiatry, 2024 - Springer
Background Existing evidence suggests that alterations in the gut microbiome are closely
associated with major depressive disorder (MDD). We aimed to reveal the causal …

Relationships between the gut microbiome and brain functional alterations in first-episode, drug-naïve patients with major depressive disorder

D Wang, X Jiang, H Zhu, Y Zhou, L Jia, Q Sun… - Journal of Affective …, 2024 - Elsevier
Objective Increasing evidence has shown that the microbiota-gut-brain axis (MGB) is
involved in the mechanism of major depressive disorder (MDD). However, the relationship …

A novel 3D-printed batch injection analysis (BIA) cell coupled to paper-based electrochemical devices: A cheap and reliable analytical system for fast on-site analysis

ME da Silva Ferreira, NC de Moraes, VS Ferreira… - Microchemical …, 2022 - Elsevier
This work reports, for the first time, the association of electrochemical paper analytical
devices (ePADs) with batch injection analysis (BIA) systems. The novel 3D-printed BIA cell …

based electrochemical platform modified with graphene nanoribbons: A new and affordable approach for analysis of 5-hydroxy-l-tryptophan

NC de Moraes, JM Petroni, F de Lima, VS Ferreira… - Microchemical …, 2022 - Elsevier
Here, a new and inexpensive electrochemical paper-based analytical device (ePAD)
containing a pencil-drawn three-electrode setup, in which the working electrode was …