The prodrug concept has been used to improve undesirable properties of drugs since the late 19th century, although it was only at the end of the 1950s that the actual term prodrug …
G Kalyana Chakravarthi, S Vijayaraj, A Venugopal… - academia.edu
Solubility is one of the essential parameters to achieve bioavailability of drug in systemic circulation to produce expected therapeutic response. Nearly 40% of new drug molecules …
VS Tegeli, YS Thorat, GK Chougule, US Shivsharan… - academia.edu
In the past few decades, Prodrug has been extensively and successfully used as a chemical tool for modification of the physicochemical, pharmacokinetic as well as pharmacodynamic …