Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020 - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery

N Habibi, N Kamaly, A Memic, H Shafiee - Nano today, 2016 - Elsevier
Self-assembly of peptides can yield an array of well-defined nanostructures that are highly
attractive nanomaterials for many biomedical applications such as drug delivery. Some of …

Elastin-like polypeptides for biomedical applications

AK Varanko, JC Su, A Chilkoti - Annual review of biomedical …, 2020 - annualreviews.org
Elastin-like polypeptides (ELPs) are stimulus-responsive biopolymers derived from human
elastin. Their unique properties—including lower critical solution temperature phase …

Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers

FG Quiroz, A Chilkoti - Nature materials, 2015 - nature.com
Proteins and synthetic polymers that undergo aqueous phase transitions mediate self-
assembly in nature and in man-made material systems. Yet little is known about how the …

Applications of elastin-like polypeptides in drug delivery

SR MacEwan, A Chilkoti - Journal of Controlled Release, 2014 - Elsevier
Elastin-like polypeptides (ELPs) are biopolymers inspired by human elastin. Their lower
critical solution temperature phase transition behavior and biocompatibility make them …

Implications of protein-and peptide-based nanoparticles as potential vehicles for anticancer drugs

AO Elzoghby, MM Elgohary, NM Kamel - Advances in protein chemistry …, 2015 - Elsevier
Protein-based nanocarriers have gained considerable attention as colloidal carrier systems
for the delivery of anticancer drugs. Protein nanocarriers possess various advantages …

Recombinant protein-based injectable materials for biomedical applications

CG Garcia, SS Patkar, B Wang, R Abouomar… - Advanced Drug Delivery …, 2023 - Elsevier
Injectable nanocarriers and hydrogels have found widespread use in a variety of biomedical
applications such as local and sustained biotherapeutic cargo delivery, and as cell …

Elastin-like polypeptides in drug delivery

JC Rodríguez-Cabello, FJ Arias, MA Rodrigo… - Advanced drug delivery …, 2016 - Elsevier
The use of recombinant elastin-like materials, or elastin-like recombinamers (ELRs), in drug-
delivery applications is reviewed in this work. Although ELRs were initially used in similar …

Protein phase separation arising from intrinsic disorder: first-principles to bespoke applications

DM Shapiro, M Ney, SA Eghtesadi… - The Journal of Physical …, 2021 - ACS Publications
The phase separation of biomolecules has become the focus of intense research in the past
decade, with a growing body of research implicating this phenomenon in essentially all …

Smart polymers in drug delivery systems on crossroads: Which way deserves following?

M Hrubý, SK Filippov, P Štěpánek - European Polymer Journal, 2015 - Elsevier
A feature article is presented on recent developments in the investigation of stimuli
responsive polymers and their biomedical applications. Polymer systems are grouped with …