[HTML][HTML] Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review
The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …
Nectin cell adhesion molecule-4 (NECTIN-4): a potential target for cancer therapy
Abstract NECTIN-4 [a poliovirus receptor-related-4 (pvrl-4) encoded protein] is a Ca 2+
independent immunoglobulin-like protein. Along with other Nectins (Nectin-1,-2 and-3), it is …
independent immunoglobulin-like protein. Along with other Nectins (Nectin-1,-2 and-3), it is …
Nano formulated Resveratrol inhibits metastasis and angiogenesis by reducing inflammatory cytokines in oral cancer cells by targeting tumor associated …
Tumor associated macrophages in the tumor microenvironment secrete multiple cytokines,
which regulate cancer cells growth and invasiveness. We systematically studied the role of …
which regulate cancer cells growth and invasiveness. We systematically studied the role of …
Quinacrine inhibits HIF-1α/VEGF-A mediated angiogenesis by disrupting the interaction between cMET and ABCG2 in patient-derived breast cancer stem cells
Background Breast cancer stem cells (BCSCs) have a critical role in progression of breast
cancer by inducing angiogenesis. Several therapeutic strategies have been designed for the …
cancer by inducing angiogenesis. Several therapeutic strategies have been designed for the …
The anti-nectin 4: a promising tumor cells target. A systematic review
W Bouleftour, A Guillot, N Magne - Molecular cancer therapeutics, 2022 - AACR
The Nectin cell adhesion protein 4 (Nectin-4) is overexpressed in multiple human
malignancies. Such aberrant expression is correlated with cancer progression and poor …
malignancies. Such aberrant expression is correlated with cancer progression and poor …
Combination therapy as a promising way to fight oral cancer
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …
Curcumin and analogues against head and neck cancer: from drug delivery to molecular mechanisms
C Zhao, X Zhou, Z Cao, L Ye, Y Cao, J Pan - Phytomedicine, 2023 - Elsevier
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the most life-
threatening diseases which also causes economic burden worldwide. To overcome the …
threatening diseases which also causes economic burden worldwide. To overcome the …
Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly (ADP-Ribose) Polymerase for BRCA Wild …
Y Li, Y Liu, D Zhang, J Chen, G Yang… - Journal of Medicinal …, 2023 - ACS Publications
Poly (ADP-ribose) polymerase (PARP) inhibitors have been approved for the treatment of
breast cancer (BC) with breast cancer susceptibility (BRCA) gene mutation. Leveraging new …
breast cancer (BC) with breast cancer susceptibility (BRCA) gene mutation. Leveraging new …
Cancer-Associated Fibroblasts Promote Migration and Invasion of Non-Small Cell Lung Cancer Cells via miR-101-3p Mediated VEGFA Secretion and AKT/eNOS …
X Guo, M Chen, L Cao, Y Hu, X Li, Q Zhang… - Frontiers in cell and …, 2021 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are major component of tumor microenvironment
(TME), which plays crucial roles in tumor growth, invasion and metastasis; however, the …
(TME), which plays crucial roles in tumor growth, invasion and metastasis; however, the …
Olaparib enhances the Resveratrol-mediated apoptosis in breast cancer cells by inhibiting the homologous recombination repair pathway
Although sensitization of BRCA-mutated, homologous recombination (HR)-deficient breast
cancer cells through PARP inhibitor is widely studied, not much is known about the …
cancer cells through PARP inhibitor is widely studied, not much is known about the …