Epithelial-mesenchymal interactions guide tooth development through its early stages and
establish the morphology of the dentin surface upon which enamel will be deposited …

We present novel findings on sauropod bone histology that cast doubt on general
palaeohistological concepts concerning the true nature of woven bone in primary cortical …

Osteocytes form an extensive cellular network throughout the hard tissue matrix of the
skeleton, which is known to regulate skeletal structure. However due to limitations in …

Objective The factors that influence seizure timing are poorly understood, and seizure
unpredictability remains a major cause of disability. Work in chronobiology has shown that …

Growing interest in bioarchaeology and its ability to address complex questions tied to social
and biological identities in the past has led to the development of nuanced methods for …

Until recently, our understanding of the evolution of human growth and development derived
from studies of fossil juveniles that employed extant populations for both age determination …

Research on the bone histology of extant and extinct animals has a long scientific history
and an accurate description of microstructural tissues is the cornerstone of the field. Ideally …

The mammalian skeleton stores calcium and phosphate ions in bone matrix. Osteocytes in
osteocyte lacunae extend numerous dendrites into canaliculi less than a micron in diameter …

The evolutionary history of extant hominoids (humans and apes) remains poorly understood.
The African fossil record during the crucial time period, the Miocene epoch, largely …

The morphologies of individual bones are crucial for their functions within the skeleton, and
vary markedly during evolution. Recent studies have begun to reveal the detailed molecular …