Cancer-associated cachexia—understanding the tumour macroenvironment and microenvironment to improve management

JM Argilés, FJ López-Soriano, B Stemmler… - Nature Reviews …, 2023 - nature.com
Cachexia is a devastating, multifactorial and often irreversible systemic syndrome
characterized by substantial weight loss (mainly of skeletal muscle and adipose tissue) that …

Sarcopenia: how to measure, when and why

AS Tagliafico, B Bignotti, L Torri, F Rossi - La radiologia medica, 2022 - Springer
Sarcopenia indicates a loss of skeletal muscle mass, a condition that leads to a decline in
physical performance. In 2018, the European Working Group on Sarcopenia in Older People …

Metabolic syndrome and sarcopenia

H Nishikawa, A Asai, S Fukunishi, S Nishiguchi… - Nutrients, 2021 - mdpi.com
Skeletal muscle is a major organ of insulin-induced glucose metabolism. In addition, loss of
muscle mass is closely linked to insulin resistance (IR) and metabolic syndrome (Met-S) …

Value-added opportunistic CT screening: state of the art

PJ Pickhardt - Radiology, 2022 - pubs.rsna.org
Opportunistic CT screening leverages robust imaging data embedded within abdominal and
thoracic scans that are generally unrelated to the specific clinical indication and have …

[HTML][HTML] Advances in muscle health and nutrition: a toolkit for healthcare professionals

CM Prado, F Landi, STH Chew, PJ Atherton, J Molinger… - Clinical Nutrition, 2022 - Elsevier
Low muscle mass and malnutrition are prevalent conditions among adults of all ages, with
any body weight or body mass index, and with acute or chronic conditions, including COVID …

Sarcopenia predicts worse postoperative outcomes and decreased survival rates in patients with colorectal cancer: a systematic review and meta-analysis

M Trejo-Avila, K Bozada-Gutiérrez… - International journal of …, 2021 - Springer
Purpose Previous studies have shown an association of sarcopenia with adverse short-and
long-term outcomes in multiple gastrointestinal cancer types. We aimed to investigate the …

Association of low muscle mass and low muscle radiodensity with morbidity and mortality for colon cancer surgery

J Xiao, BJ Caan, EMC Feliciano, JA Meyerhardt… - JAMA …, 2020 - jamanetwork.com
Importance Given the risks of postoperative morbidity and its consequent economic burden
and impairment to patients undergoing colon resection, evaluating risk factors associated …

Computed tomography‐defined low skeletal muscle index and density in cancer patients: observations from a systematic review

J McGovern, RD Dolan, PG Horgan… - Journal of cachexia …, 2021 - Wiley Online Library
Background Computed tomography (CT) analysis of body composition has garnered interest
as a potential prognostic tool in those with cancer. A range of pre‐defined thresholds …

Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient

CM Prado, KL Ford, MC Gonzalez… - Journal of Parenteral …, 2023 - Wiley Online Library
Preoperative nutrition status is an important determinant of surgical outcomes, yet
malnutrition assessment is not integrated into all surgical pathways. Given its importance …

Examining guidelines and new evidence in oncology nutrition: a position paper on gaps and opportunities in multimodal approaches to improve patient care

CM Prado, A Laviano, C Gillis, AD Sung… - Supportive Care in …, 2022 - Springer
Malnutrition, muscle loss, and cachexia are prevalent in cancer and remain key challenges
in oncology today. These conditions are frequently underrecognized and undertreated and …