Review of the current state of protein aggregation inhibition from a materials chemistry perspective: Special focus on polymeric materials

R Rajan, S Ahmed, N Sharma, N Kumar, A Debas… - Materials …, 2021 - pubs.rsc.org
Protein instability caused by exposure to external additives or severe stress may result in
different diseases. Of these diseases, many are triggered by protein misfolding and …

Protecting Proteins from Desiccation Stress Using Molecular Glasses and Gels

GI Olgenblum, BO Hutcheson, GJ Pielak… - Chemical …, 2024 - ACS Publications
Faced with desiccation stress, many organisms deploy strategies to maintain the integrity of
their cellular components. Amorphous glassy media composed of small molecular solutes or …

Freeze-drying of platelet-rich plasma: the quest for standardization

I Andia, A Perez-Valle, C Del Amo… - International journal of …, 2020 - mdpi.com
The complex biology of platelets and their involvement in tissue repair and inflammation
have inspired the development of platelet-rich plasma (PRP) therapies for a broad array of …

Frozen and freeze‐dried solvent/detergent treated plasma: Two different pharmaceutical formulations with comparable quality

A Heger, G Gruber - Transfusion, 2022 - Wiley Online Library
Background OctaplasLG is a frozen solvent/detergent‐treated plasma product used for
treating complex coagulation factor deficiencies or as substitution therapy in emergency …

Bacteriophage entrapped chitosan microgel for the treatment of biofilm-mediated polybacterial infection in burn wounds

D Dehari, DN Kumar, A Chaudhuri, A Kumar… - International Journal of …, 2023 - Elsevier
Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) bacteria
are most commonly present in burn wound infections. Multidrug resistance (MDR) and …

Ex vivo hemostatic and immuno‐inflammatory profiles of freeze‐dried plasma

HT Peng, SG Rhind, D Devine, C Jenkins… - Transfusion, 2021 - Wiley Online Library
Background Hemorrhage is a leading cause of preventable death in civilian and military
trauma. Freeze‐dried plasma is promising for hemostatic resuscitation in remote prehospital …

Storage conditions affect the composition of the lyophilized secretome of multipotent mesenchymal stromal cells

O Rogulska, I Vackova, S Prazak, K Turnovcova… - Scientific Reports, 2024 - nature.com
The widespread use of multipotent mesenchymal stromal cell-derived secretome (MSC-sec)
requires optimal preservation methods. Lyophilization offers benefits like concentrating the …

Shipping and logistics considerations for regenerative medicine therapies

T Criswell, C Swart, J Stoudemire… - Stem Cells …, 2022 - academic.oup.com
Advances in regenerative medicine manufacturing continue to be a priority for achieving the
full commercial potential of important breakthrough therapies. Equally important will be the …

Establishing an efficient membrane bioreactor for simultaneous pollutant removal and purple bacteria production under salinity stress

T Hao, Y Xu, C Liang, X Peng, S Yu, L Peng - Chemosphere, 2024 - Elsevier
Recovering resources from wastewater to alleviate the energy crisis has become the
prevailing trend of technological development. Purple phototrophic bacteria (PPB), a group …

[HTML][HTML] The Biological Effect of Enriching the Plasma Content in Platelet-Rich Plasma: An In Vitro Study

E Anitua, M Zalduendo, R Prado, M Troya… - …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND: Platelet-rich plasma (PRP) formulations have become valuable therapeutic
tools in regenerative medicine. In addition, these blood derivates have been successfully …