Plague is one of the world's most lethal human diseases caused by Yersinia pestis, a Gram-
negative bacterium. Despite overwhelming studies for many years worldwide, there is no …

The potential application of Yersinia pestis for bioterrorism emphasizes the urgent need to
develop more effective vaccines against airborne infection. The current status of plague …

Pneumonic plague is a highly virulent infectious disease with 100% mortality rate, and its
causative organism Yersinia pestis poses a serious threat for deliberate use as a bioterror …

An opportunity exists today for cross-cutting research utilizing advances in materials
science, immunology, microbial pathogenesis and computational analysis to effectively …

Plague, caused by the bacterial pathogen Yersinia pestis, is a vector-borne disease that has
caused millions of human deaths over several centuries. Presently, human plague infections …

Yersinia pestis (YP), the gram-negative plague bacterium, has shaped human history unlike
any other pathogen known to mankind. YP (transmitted by the bite of an infected flea) …

Madagascar has just emerged from the grip of an acute urban pneumonic plague outbreak,
which began in August 2017, before the usual plague season of October–April and outside …

Immunization with the Yersinia pestis F1 and LcrV proteins improves survival in mouse and
non-human primate models of pneumonic plague. F1-and LcrV-specific antibodies …

Relatively recent advances in plague vaccinology have produced the recombinant fusion
protein F1-V plague vaccine. This vaccine has been shown to readily protect mice from both …

Yersinia pestis is the causative agent of plague and is a re-emerging pathogen that also has
the potential as a biological weapon, necessitating the development of a preventive vaccine …