[HTML][HTML] Alkaloids from traditional Chinese medicine against hepatocellular carcinoma

C Liu, S Yang, K Wang, X Bao, Y Liu, S Zhou… - Biomedicine & …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) has become one of the major diseases that are threatening
human health in the 21st century. Currently there are many approaches to treat liver cancer …

A comprehensive review on pharmacokinetic mechanism of herb-herb/drug interactions in Chinese herbal formula

M Li, Y Wang, Y Chen, L Dong, J Liu, Y Dong… - Pharmacology & …, 2024 - Elsevier
Abstract Oral administration of Chinese Herbal Medicine (CHM) faces various challenges in
reaching the target organs including absorption and conversion in the gastrointestinal tract …

Research progress and challenges of TRPV1 channel modulators as a prospective therapy for diabetic neuropathic pain

C Liu, R Miao, F Raza, H Qian, X Tian - European Journal of Medicinal …, 2023 - Elsevier
Diabetic neuropathic pain (DNP) is a common, complex, and severe complication of
diabetes. It can lead to increased mortality, lower-limb amputations, and distressing …

Phytochemicals that interfere with drug metabolism and transport, modifying plasma concentration in humans and animals

J Gómez-Garduño, R León-Rodríguez… - Dose …, 2022 - journals.sagepub.com
Phytochemicals (Pch) present in fruits, vegetables and other foods, are known to inhibit or
induce drug metabolism and transport. An exhaustive search was performed in five …

[HTML][HTML] Personalized medicine of non-gene-specific chemotherapies for non-small cell lung cancer

W Jiang, G Cai, P Hu, Y Wang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Non-small cell lung cancer is recognized as the deadliest cancer across the globe. In some
areas, it is more common in women than even breast and cervical cancer. Its rise, vaulted by …

[HTML][HTML] Modulation of multidrug resistance transporters by food components and dietary supplements: implications for cancer therapy efficacy and safety

A Brodzicka, A Galanty, P Paśko - Current Issues in Molecular Biology, 2024 - mdpi.com
The aim of this review is to explore how diet and dietary supplements influence the activity of
key multidrug resistance (MDR) transporters—MRP2, BCRP, and P-gp. These transporters …

A systematic literature review (SLR): evaluation pharmacokinetic profile of drug combined p-glycoprotein (p-gp) alkaloid inhibitor in white rats (rattus norvegicus)

A Yugatama, H Rahmawati… - Journal of Physics …, 2021 - iopscience.iop.org
Abstract P-glycoprotein (P-gp) is a protein transporter as an active efflux pump of many
xenobiotics. P-gp plays an important role in the pharmacokinetic process that it will affect the …