During pregnancy and lactation, female physiology adapts to meet the added nutritional
demands of fetuses and neonates. An average full-term fetus contains∼ 30 g calcium, 20 g …

Maternal-Fetal Calcium and Bone Metabolism During Pregnancy, Puerperium, and
Lactation* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement …

EDITOR-IN-CHIEF: Clifford J. Rosen, MD, Maine Medical Center Research Institute,
Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, MD, FRCP …

The placenta is essential for sustaining the growth of the fetus during gestation, and defects
in its function result in fetal growth restriction or, if more severe, fetal death. Several …

Mineral and bone metabolism are regulated differently in utero compared with the adult. The
fetal kidneys, intestines, and skeleton are not dominant sources of mineral supply for the …

Biomineralization is the process by which organisms produce mineralized tissues. This
crucial process makes possible the rigidity and flexibility that the skeleton needs for …

PTHrP was identified as a cause of hypercalcemia in cancer patients 25 yr ago. In the
intervening years, we have learned that PTHrP and PTH are encoded by related genes that …

The major mineralized tissues are bone and teeth, which share several mechanisms
governing their development and mineralization. This crossover includes the hormones that …

Pregnancy and lactation require women to mobilize calcium to provide to the offspring. A
common assumption is that higher intakes of calcium and vitamin D are required during …

Cancer and Bone* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement
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