Although active constituents extracted from plants show robust in vitro pharmacological
effects, low in vivo absorption greatly limits the widespread application of these compounds …

Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

The apigenin-phospholipid phytosome (APLC) was developed to improve the aqueous
solubility, dissolution, in vivo bioavailability, and antioxidant activity of apigenin. The APLC …

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

Post-exercise recovery is a broad term that refers to the restoration of training capacity. After
training or competition, there is fatigue accumulation and a reduction in sports performance …

Phytoconstituents have been utilized as medicines for thousands of years, yet their
application is limited owing to major hurdles like deficit lipid solubility, large molecular size …

Background: Cyclodextrins (CDs) are versatile excipients with an essential role in drug
delivery, as they can form non-covalently bonded inclusion complexes (host-guest …

A central composite design approach was applied to study the effect of polymer
concentration, inlet temperature and air flow rate on the spray drying process of the Büchi B …

Quercetin (QT) is a natural flavonoid with various biological activities and pharmacological
actions. However, the bioavailability of QT is relatively low due to its low solubility which …

Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-noneamide) is a hydrophobic, lipophilic
vanilloid phytochemical abundantly found in chili peppers and pepper extracts. Several …