Regulation of intestinal lipid metabolism: current concepts and relevance to disease

CW Ko, J Qu, DD Black, P Tso - Nature Reviews Gastroenterology & …, 2020 - nature.com
Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …

Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance

M Bionaz, E Vargas-Bello-Pérez, S Busato - Journal of Animal Science …, 2020 - Springer
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …

Intestinal lipid absorption

J Iqbal, MM Hussain - American Journal of Physiology …, 2009 - journals.physiology.org
Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has
advanced considerably. Researchers have identified several new mechanisms by which …

Bi-directional protein transport between the ER and Golgi

MCS Lee, EA Miller, J Goldberg, L Orci… - Annu. Rev. Cell Dev …, 2004 - annualreviews.org
▪ Abstract The endoplasmic reticulum (ER) and the Golgi comprise the first two steps in
protein secretion. Vesicular carriers mediate a continuous flux of proteins and lipids between …

COPII and the regulation of protein sorting in mammals

G Zanetti, KB Pahuja, S Studer, S Shim… - Nature cell …, 2012 - nature.com
Secretory proteins are transported to the Golgi complex in vesicles that bud from the
endoplasmic reticulum. The cytoplasmic coat protein complex II (COPII) is responsible for …

Recent advances in physiological lipoprotein metabolism

I Ramasamy - Clinical Chemistry and Laboratory Medicine (CCLM), 2014 - degruyter.com
Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

Intracellular trafficking and secretion of VLDL

S Tiwari, SA Siddiqi - Arteriosclerosis, thrombosis, and vascular …, 2012 - Am Heart Assoc
Steady increase in the incidence of atherosclerosis is becoming a major concern not only in
the United States but also in other countries. One of the major risk factors for the …

[HTML][HTML] Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes

C Moschandrea, V Kondylis, I Evangelakos, M Herholz… - Nature, 2024 - nature.com
Digested dietary fats are taken up by enterocytes where they are assembled into pre-
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …

Lipid transfer proteins in the assembly of apoB-containing lipoproteins

A Sirwi, MM Hussain - Journal of Lipid Research, 2018 - ASBMB
A better understanding of intracellular lipoprotein assembly may help identify proteins with
important roles in lipid disorders. apoB-containing lipoproteins (B-lps) are macromolecular …

The biogenesis of chylomicrons

CM Mansbach, SA Siddiqi - Annual review of physiology, 2010 - annualreviews.org
The absorption of dietary fat is of increasing concern given the rise of obesity not only in the
United States but throughout the developed world. This review explores what happens to …