Chemistry, Nutrition, and Microbiology of d-Amino Acids

M Friedman - Journal of Agricultural and Food Chemistry, 1999 - ACS Publications
Exposure of food proteins to certain processing conditions induces two major chemical
changes: racemization of all l-amino acids to d-isomers and concurrent formation of cross …

D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role

A D'Aniello - Brain research reviews, 2007 - Elsevier
d-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and
invertebrates, plays an important role in the neuroendocrine system, as well as in the …

The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats

E Topo, A Soricelli, A D'Aniello, S Ronsini… - Reproductive Biology …, 2009 - Springer
Background D-aspartic acid is an amino acid present in neuroendocrine tissues of
invertebrates and vertebrates, including rats and humans. Here we investigated the effect of …

Occurrence of D‐aspartic acid and N‐methyl‐D‐aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth …

AD‧ Aniello, MM Di Fiore, GH Fisher… - The FASEB …, 2000 - Wiley Online Library
Using two specific and sensitive fluorometric/HPLC methods and a GC‐MS method, alone
and in combination with D‐aspartate oxidase, we have demonstrated for the first time that N …

Novel neurotransmitters and their neuropsychiatric relevance

SH Snyder, CD Ferris - American Journal of Psychiatry, 2000 - Am Psychiatric Assoc
OBJECTIVE: The purpose of this review is to integrate insights regarding novel
neurotransmitters or neuromodulators of neuropsychiatric significance. METHOD: Evolving …

Origin, Microbiology, Nutrition, and Pharmacology of D‐Amino Acids

M Friedman - Chemistry & biodiversity, 2010 - Wiley Online Library
Exposure of food proteins to certain processing conditions induces two major chemical
changes: racemization of all l‐amino acids (LAAs) to d‐amino acids (DAAs) and concurrent …

A sensitive and simple ultra-high-performance-liquid chromatography–tandem mass spectrometry based method for the quantification of d-amino acids in body fluids

WF Visser, NM Verhoeven-Duif, R Ophoff… - … of Chromatography A, 2011 - Elsevier
d-Amino acids are increasingly being recognized as important signaling molecules in
mammals, including humans. d-Serine and d-aspartate are believed to act as signaling …

[HTML][HTML] D-aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release

H Wolosker, A D'aniello, SH Snyder - Neuroscience, 2000 - Elsevier
High levels of d-aspartate occur in the brain and endocrine glands, such as pineal, adrenal
and pituitary. In the brain, d-aspartate levels are highest in embryonic and early postnatal …

D‐Aspartic acid is a novel endogenous neurotransmitter

S D'Aniello, I Somorjai, J Garcia‐Fernàndez… - The FASEB …, 2011 - Wiley Online Library
D‐Aspartic acid (D‐Asp) is present in invertebrate and vertebrate neuroendocrine tissues'
where it carries out important physiological functions and is implicated in nervous system …

The Role of d-Aspartic Acid and N-Methyl-d-Aspartic Acid in the Regulation of Prolactin Release

G D'Aniello, A Tolino, A D'aniello, F Errico… - …, 2000 - academic.oup.com
In this study, using an enzymatic HPLC method in combination with d-aspartate oxidase, we
show that N-methyl-d-aspartate (NMDA) is present at nanomolar levels in rat nervous …