Vascular smooth muscle cells phenotypic switching in cardiovascular diseases

HY Tang, AQ Chen, H Zhang, XF Gao, XQ Kong… - Cells, 2022 - mdpi.com
Vascular smooth muscle cells (VSMCs), the major cell type in the arterial vessel wall, have a
contractile phenotype that maintains the normal vessel structure and function under …

NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives

GR Navale, S Singh, K Ghosh - Coordination Chemistry Reviews, 2023 - Elsevier
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …

Platelet-derived porous nanomotor for thrombus therapy

M Wan, Q Wang, R Wang, R Wu, T Li, D Fang… - Science …, 2020 - science.org
The treatment difficulties of venous thrombosis include short half-life, low utilization, and
poor penetration of drugs at thrombus site. Here, we develop one kind of mesoporous …

Polymeric nitric oxide delivery nanoplatforms for treating cancer, cardiovascular diseases, and infection

G Jin, Z Gao, Y Liu, J Zhao, H Ou… - Advanced Healthcare …, 2021 - Wiley Online Library
The shortened Abstract is as follows: Therapeutic gas nitric oxide (NO) has demonstrated
the unique advances in biomedical applications due to its prominent role in regulating …

Hypersensitivity and in-stent restenosis in coronary stent materials

W Hu, J Jiang - Frontiers in bioengineering and biotechnology, 2022 - frontiersin.org
Coronary heart disease (CHD) is a type of cardiovascular disease with the highest mortality
rate worldwide. Percutaneous transluminal coronary intervention (PCI) is the most effective …

[HTML][HTML] Intimal hyperplasia of arteriovenous fistula

S Ma, S Duan, Y Liu, H Wang - Annals of Vascular Surgery, 2022 - Elsevier
Intimal hyperplasia (IH), a crucial histopathological injury, forms the basis of vascular
stenosis and thrombogenesis. In addition, it is common in maladies such as stenosis at the …

Efficient differentiation of human induced pluripotent stem cells into endothelial cells under xenogeneic-free conditions for vascular tissue engineering

J Luo, X Shi, Y Lin, Y Yuan, MH Kural, J Wang… - Acta biomaterialia, 2021 - Elsevier
Tissue engineered vascular grafts (TEVGs) represent a promising therapeutic option for
emergency vascular intervention. Although the application of small-diameter TEVGs using …

3D-Printed Stents Loaded with Panax notoginseng Saponin for Promoting Re-endothelialization and Reducing Local Inflammation in the Carotid Artery of Rabbits

C Tang, Y Shen, Y Xing, Y Wu, M Zhang… - ACS Biomaterials …, 2024 - ACS Publications
Endovascular treatment (EVT) using stents has become the primary option for severe
cerebrovascular stenosis. However, considerable challenges remain to be addressed, such …

Therapeutic approaches targeting CD95L/CD95 signaling in cancer and autoimmune diseases

V Risso, E Lafont, M Le Gallo - Cell death & disease, 2022 - nature.com
Cell death plays a pivotal role in the maintenance of tissue homeostasis. Key players in the
controlled induction of cell death are the Death Receptors (DR). CD95 is a prototypic DR …

Adaptation of Vascular Smooth Muscle Cell to Degradable Metal Stent Implantation

M Wu, M Xun, Y Chen - ACS Biomaterials Science & Engineering, 2023 - ACS Publications
Iron-, magnesium-, or zinc-based metal vessel stents support vessel expansion at the period
early after implantation and degrade away after vascular reconstruction, eliminating the side …